TRKA Antikörper (AA 769-796)

Produktnummer ABIN3031984

Produktdetails anti-TRKA Antikörper

Target: TRKA (NTRK1) (Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1))

Bindungsspezifität: AA 769-796

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRKA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 769-796 from the human protein was used as the immunogen for this TrkA antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the TrkA antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50,IHC (Paraffin): 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the TrkA antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu TRKA

Target: TRKA (NTRK1) (Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1))

Andere Bezeichnung: TrkA (NTRK1 Produkte)

Synonyme: MTC antikoerper, TRK antikoerper, TRK1 antikoerper, TRKA antikoerper, Trk-A antikoerper, p140-TrkA antikoerper, CDHF12 antikoerper, CDHR16 antikoerper, HSCR1 antikoerper, MEN2A antikoerper, MEN2B antikoerper, MTC1 antikoerper, PTC antikoerper, RET-ELE1 antikoerper, RET51 antikoerper, Trk antikoerper, C80751 antikoerper, Tkr antikoerper, TrkA antikoerper, trk antikoerper, trka antikoerper, CTRKA antikoerper, trkA antikoerper, neurotrophic receptor tyrosine kinase 1 antikoerper, ret proto-oncogene antikoerper, neurotrophic tyrosine kinase, receptor, type 1 antikoerper, NTRK1 antikoerper, RET antikoerper, Ntrk1 antikoerper, ntrk1 antikoerper

Hintergrund: TRKA (also known as NTRK1)is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in the TRKA gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.

UniProt: P04629

Pathways: RTK Signalweg, Neurotrophin Signalübertragung, cAMP Metabolic Process