FGFR1 Antikörper (AA 837-852)

Produktnummer ABIN364422

Produktdetails anti-FGFR1 Antikörper

Target: FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))

Bindungsspezifität: AA 837-852

Reaktivität: Human, Rind (Kuh), Hund, Affe, Pferd, Fledermaus

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser FGFR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Marke: IHC-plus™

Spezifität: Human FGFR1. This antibody is expected to recognise five isoforms (as represented by NP_075598.2, NP_056934.2, NP_075593.1, NP_075594.1, NP_075599.1).

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Elephant, Panda, Bovine, Dog, Bat, Horse, Platypus (100%) Rat, Hamster, Pig, Opossum (94%) Mouse, Rabbit (88%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide CLPRHPAQLANGGLKR from the C-terminus of human FGFR1 (NP_075598.2, NP_056934.2, NP_075593.1, NP_075594.1, NP_075599.1). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Elephant, Panda, Bovine, Dog, Bat, Horse, Platypus (100%), Rat, Hamster, Pig, Opossum (94%), Mouse, Rabbit (88%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (4 μg/mL), Peptide-ELISA (1:32000), WB (0.3 - 1 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 4 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze-thaw cycles.

Details zu FGFR1

Target: FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))

Andere Bezeichnung: FGFR1 (FGFR1 Produkte)

Synonyme: FGFR antikoerper, fgfr antikoerper, X1FGFR antikoerper, XFGFR-1 antikoerper, XFGFRA2 antikoerper, bfgfr antikoerper, cek antikoerper, fgfr1 antikoerper, flg antikoerper, flt-2 antikoerper, flt2 antikoerper, kal2 antikoerper, ogd antikoerper, xfgfr1 antikoerper, CG7223 antikoerper, CT22273 antikoerper, CT39172 antikoerper, DFGF-R1 antikoerper, DFGF-R2 antikoerper, DFR-1 antikoerper, DFR1 antikoerper, DFR1/DFGF-R2 antikoerper, DPR3 antikoerper, DTRK(FR1) antikoerper, Dfr-1 antikoerper, Dfr1 antikoerper, DmHD-38 antikoerper, Dmel\\CG7223 antikoerper, Dtk1 antikoerper, EMS2 antikoerper, FGF-R2 antikoerper, FGFR2 antikoerper, FR1 antikoerper, Fr1 antikoerper, HD-38 antikoerper, HTL/FGFR1 antikoerper, Htl antikoerper, Tk1 antikoerper, dtk1 antikoerper, i100 antikoerper, i150 antikoerper, i79 antikoerper, j372 antikoerper, cd331 antikoerper, fgfbr antikoerper, fgfr-1 antikoerper, hbgfr antikoerper, n-sam antikoerper, ach antikoerper, cd333 antikoerper, cek2 antikoerper, fgfr-3 antikoerper, hsfgfr3ex antikoerper, jtk4 antikoerper, BFGFR antikoerper, CD331 antikoerper, CEK antikoerper, FGFBR antikoerper, FGFR-1 antikoerper, FLG antikoerper, FLT-2 antikoerper, FLT2 antikoerper, HBGFR antikoerper, HH2 antikoerper, KAL2 antikoerper, N-SAM antikoerper, OGD antikoerper, bFGF-R-1 antikoerper, AW208770 antikoerper, Eask antikoerper, Fgfr-1 antikoerper, Flt-2 antikoerper, Hspy antikoerper, FLG-1 antikoerper, FGFRI antikoerper, x1fgfr antikoerper, cb231 antikoerper, sb:cb231 antikoerper, fibroblast growth factor receptor antikoerper, fibroblast growth factor receptor 1 S homeolog antikoerper, basic fibroblast growth factor receptor 1 antikoerper, heartless antikoerper, fibroblast growth factor receptor 1 antikoerper, fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) L homeolog antikoerper, Fibroblast growth factor receptor 1 antikoerper, fibroblast growth factor receptor 1 L homeolog antikoerper, fibroblast growth factor receptor 1a antikoerper, FGFR antikoerper, fgfr antikoerper, fgfr1.S antikoerper, CpipJ_CPIJ005849 antikoerper, htl antikoerper, fgfr1 antikoerper, fgfr3.L antikoerper, FGFR1 antikoerper, Fgfr1 antikoerper, fgfr1.L antikoerper, fgfr1a antikoerper

Hintergrund: Name/Gene ID: FGFR1
Subfamily: FGF Receptor
Family: Protein Kinase

Synonyms: FGFR1, BFGF receptor, BFGF-R, BFGF-R-1, CD331, Cek1, CD331 antigen, FGFR1/PLAG1 fusion, FLT2, Fgf-flg, FGFBR, FGFR-1, Fms-like tyrosine kinase 2, HBGFR, HH2, Hydroxyaryl-protein kinase, FGF receptor 1, Fms-related tyrosine kinase 2, Proto-oncogene c-Fgr, BFGFR, CEK, FLT-2, HBGF receptor, KAL2, OGD

Gen-ID: 2260

NCBI Accession: NP_075598, NP_056934, NP_075593, NP_075594, NP_075599

UniProt: P11362

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Sensory Perception of Sound, Stem Cell Maintenance, S100 Proteine