FGFR1 Produkte
(Fibroblast Growth Factor Receptor 1 (FGFR1))
Kategorien
The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2. Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome. Alternatively spliced variants which encode different protein isoforms have been described\; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008].
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Ausgewählte FGFR1 Kategorien
FGFR1 Antikörper
High quality antibodies with extensive validation data.
FGFR1 ELISA Kits
Reliable ELISA kits for a wide range of species.
FGFR1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene FGFR1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IF, IHC (p), FACS
Validierungen
- (12)
- (4)
Kat. Nr.
ABIN1882081
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (5)
Kat. Nr.
ABIN7434056
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC, IF, ICC
Validierungen
- (5)
Kat. Nr.
ABIN6261731
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene FGFR1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (2)
- (1)
Kat. Nr.
ABIN6955877
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6966791
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6966790
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene FGFR1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7274633
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect cells (Sf9)
Validierungen
- (2)
Kat. Nr.
ABIN5570013
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7122955
Menge
50 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren FGFR1 Produkten
: "Fibroblast growth factor-2/platelet-derived growth factor enhances atherosclerotic plaque stability." in: Journal of cellular and molecular medicine, Vol. 24, Issue 1, pp. 1128-1140, (2020) (PubMed).: "Fibroblast growth factor 21 ameliorates vascular calcification by inhibiting osteogenic transition in vitamin D3 plus nicotine-treated rats." in: Biochemical and biophysical research communications, Vol. 495, Issue 4, pp. 2448-2455, (2018) (PubMed).
: "Protection Effect of Exogenous Fibroblast Growth Factor 21 on the Kidney Injury in Vascular Calcification Rats." in: Chinese medical journal, Vol. 131, Issue 5, pp. 532-538, (2018) (PubMed).
: "Role and regulation of growth plate vascularization during coupling with osteogenesis in tibial dyschondroplasia of chickens." in: Scientific reports, Vol. 8, Issue 1, pp. 3680, (2018) (PubMed).
: "Fibroblast growth factor receptor-1 mediates internalization of pathogenic spotted fever rickettsiae into host endothelium." in: PLoS ONE, Vol. 12, Issue 8, pp. e0183181, (2017) (PubMed).
: "Synergistic suppression of a disintegrin acurhagin-C in combination with AZD4547 and reparixin on terminating development for human osteosarcoma MG-63 cell." in: Biochemical and biophysical research communications, Vol. 492, Issue 3, pp. 513-519, (2017) (PubMed).
: "Association of fibroblast growth factor receptor 1 gene amplification with poor survival in patients with esophageal squamous cell carcinoma." in: Oncotarget, Vol. 8, Issue 51, pp. 88857-88869, (2017) (PubMed).
: "TDP-43 loss of function inhibits endosomal trafficking and alters trophic signaling in neurons." in: The EMBO journal, Vol. 35, Issue 21, pp. 2350-2370, (2016) (PubMed).
: "Combination treatment of prostate cancer with FGF receptor and AKT kinase inhibitors." in: Oncotarget, Vol. 8, Issue 4, pp. 6179-6192, (2016) (PubMed).
: "Homeobox family Hoxc localization during murine palate formation." in: Congenital anomalies, Vol. 56, Issue 4, pp. 172-9, (2016) (PubMed).
Synonyme und alternative Namen zu FGFR1
fibroblast growth factor receptor (FGFR), fibroblast growth factor receptor (fgfr), fibroblast growth factor receptor 1 S homeolog (fgfr1.S), basic fibroblast growth factor receptor 1 (CpipJ_CPIJ005849), heartless (htl), fibroblast growth factor receptor 1 (fgfr1), fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) L homeolog (fgfr3.L), fibroblast growth factor receptor 1 (FGFR1), fibroblast growth factor receptor 1 (Fgfr1), Fibroblast growth factor receptor 1 (Fgfr1), fibroblast growth factor receptor 1 L homeolog (fgfr1.L), fibroblast growth factor receptor 1a (fgfr1a), ach, AW208770, bFGF-R-1, bfgfr, BFGFR, cb231, cd331, CD331, cd333, cek, CEK, cek2, CG7223, CT22273, CT39172, DFGF-R1, DFGF-R2, DFR-1, Dfr-1, DFR1, Dfr1, DFR1/DFGF-R2, Dmel\\CG7223, DmHD-38, DPR3, Dtk1, dtk1, DTRK(FR1), Eask, EMS2, FGF-R2, fgfbr, FGFBR, FGFR, fgfr, fgfr-1, FGFR-1, Fgfr-1, fgfr-3, fgfr1, FGFR2, FGFRI, flg, FLG, FLG-1, flt-2, FLT-2, Flt-2, flt2, FLT2, FR1, Fr1, hbgfr, HBGFR, HD-38, HH2, hsfgfr3ex, Hspy, Htl, HTL/FGFR1, i79, i100, i150, j372, jtk4, kal2, KAL2, n-sam, N-SAM, ogd, OGD, sb:cb231, Tk1, X1FGFR, x1fgfr, XFGFR-1, xfgfr1, XFGFRA2Bezeichner auf Proteinebene für FGFR1
- fibroblast growth factor receptor
- FGFR-1
- fibroblast growth factor receptor-1
- basic fibroblast growth factor receptor 1
- CG7223-PA
- CG7223-PB
- CG7223-PC
- FGF receptor
- fibroblast growth factor receptor 1
- htl-PA
- htl-PB
- htl-PC
- fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome)
- ibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome)
- basic fibroblast growth factor receptor 1-like
- FGFR1/PLAG1 fusion
- FMS-like tyrosine kinase 2
- fms-related tyrosine kinase 2
- heparin-binding growth factor receptor
- hydroxyaryl-protein kinase
- proto-oncogene c-Fgr
- MFR
- bFGF-R-1
- c-fgr
- FGF receptor-1
- bFGF-R
- cek1 protein
- tyrosine kinase receptor CEK1
- FGFR-1-A
- bFGF-R-1-A
- basic fibroblast growth factor receptor 1-A
- fibroblast growth factor receptor 1-A
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