FHIT Produkte
(Fragile Histidine Triad (FHIT))
Kategorien
This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009].
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Ausgewählte FHIT Kategorien
FHIT Antikörper
High quality antibodies with extensive validation data.
FHIT ELISA Kits
Reliable ELISA kits for a wide range of species.
FHIT Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene FHIT Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (4)
Kat. Nr.
ABIN3021692
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (2)
- (4)
Kat. Nr.
ABIN3042392
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
ELISA, WB, IHC, IF, ICC
Validierungen
- (3)
Kat. Nr.
ABIN6261741
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene FHIT ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6975306
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1381137
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6951726
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene FHIT Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7123000
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1354070
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3132324
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren FHIT Produkten
: "FHIT, a Novel Modifier Gene in Pulmonary Arterial Hypertension." in: American journal of respiratory and critical care medicine, Vol. 199, Issue 1, pp. 83-98, (2019) (PubMed).: "FHIT promoter methylation status, low protein and high mRNA levels in patients with non-small cell lung cancer." in: International journal of oncology, Vol. 49, Issue 3, pp. 1175-84, (2016) (PubMed).
: "High-resolution whole-genome analysis of skull base chordomas implicates FHIT loss in chordoma pathogenesis." in: Neoplasia (New York, N.Y.), Vol. 14, Issue 9, pp. 788-98, (2012) (PubMed).
: "CpG island hypermethylation of multiple tumor suppressor genes associated with loss of their protein expression during rat lung carcinogenesis induced by 3-methylcholanthrene and diethylnitrosamine." in: Biochemical and biophysical research communications, Vol. 402, Issue 3, pp. 507-14, (2010) (PubMed).
: "Neuroprotective properties of picroside II in a rat model of focal cerebral ischemia." in: International journal of molecular sciences, Vol. 11, Issue 11, pp. 4580-90, (2010) (PubMed).
: "The protein expression of TRP-1 and galectin-1 in cutaneous malignant melanomas." in: Cancer genomics & proteomics, Vol. 5, Issue 6, pp. 293-300, (2009) (PubMed).
: "Muir-Torre-like syndrome in Fhit-deficient mice." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 9, pp. 4742-7, (2000) (PubMed).
: "The Fhit tumor suppressor protein regulates the intracellular concentration of diadenosine triphosphate but not diadenosine tetraphosphate." in: Cancer research, Vol. 60, Issue 9, pp. 2342-4, (2000) (PubMed).
: "The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers." in: Cell, Vol. 84, Issue 4, pp. 587-97, (1996) (PubMed).
: "Coxsackievirus B3: primary structure of the 5' non-coding and capsid protein-coding regions of the genome." in: Virus research, Vol. 3, Issue 3, pp. 263-70, (1986) (PubMed).
Synonyme und alternative Namen zu FHIT
fragile histidine triad (FHIT), fragile histidine triad (Fhit), fragile histidine triad gene (fhit), fragile histidine triad gene (Fhit), fragile histidine triad (fhit), fragile histidine triad protein (PY07476), fragile histidine triad L homeolog (fhit.L), AP3Aase, AW045638, FHIT, FRA3B, Fra14A2, LOC100223655, zgc:73176Bezeichner auf Proteinebene für FHIT
- AP3A hydrolase
- bis(5'-adenosyl)-triphosphatase
- diadenosine 5',5'''-P1,P3-triphosphate hydrolase
- dinucleosidetriphosphatase
- tumor suppressor protein
- AP3Aase
- fragile histidine triad protein
- fragile histidine triad gene
- diadenosine triphosphate hydrolase
- fragile histidine triad
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