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FH Produkte

(Fumarate Hydratase (FH))
The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. [provided by RefSeq, Jul 2008].

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Ausgewählte FH Kategorien

FH Antikörper

High quality antibodies with extensive validation data.

FH ELISA Kits

Reliable ELISA kits for a wide range of species.

FH Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene FH Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation ICC, IF, IHC (p), WB
Validierungen
  • (1)
  • (5)
Kat. Nr. ABIN2856710
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, EIA, IHC, WB
Validierungen
  • (5)
Kat. Nr. ABIN190758
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation ICC, IF, IHC (p), WB
Validierungen
  • (5)
Kat. Nr. ABIN2856737
Menge 100 μL
Datenblatt Datenblatt

Empfohlene FH ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6966911
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6951759
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Competition ELISA
Validierungen
Kat. Nr. ABIN773162
Menge 96 tests
Datenblatt Datenblatt

Empfohlene FH Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN3080328
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN3121250
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1354068
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren FH Produkten

Zhou, Xu, Zeng, Chen, Lu, Gong, Finnell, Xiao, Qiao, Wang: "Combined effects of FH (E404D) and ACOX2 (R409H) cause metabolic defects in primary cardiac malignant tumor." in: Cell death discovery, Vol. 4, pp. 18, (2018) (PubMed).

Miettinen, Felisiak-Golabek, Wasag, Chmara, Wang, Butzow, Lasota: "Fumarase-deficient Uterine Leiomyomas: An Immunohistochemical, Molecular Genetic, and Clinicopathologic Study of 86 Cases." in: The American journal of surgical pathology, Vol. 40, Issue 12, pp. 1661-1669, (2017) (PubMed).

Burkart, Tan, Warren, Iovino, Hughes, Kahn, Patti: "Insulin Resistance in Human iPS Cells Reduces Mitochondrial Size and Function." in: Scientific reports, Vol. 6, pp. 22788, (2016) (PubMed).

Xu, Ge, Huo, Zhang, Lau, Xu: "Differential proteomic expression of human placenta and fetal development following e-waste lead and cadmium exposure in utero." in: The Science of the total environment, Vol. 550, pp. 1163-1170, (2016) (PubMed).

Kratochvílová, Hejzlarová, Vrbacký, Mrá?ek, Karbanová, Tesa?ová, Gombitová, Cmarko, Wittig, Zeman, Houšt?k: "Mitochondrial membrane assembly of TMEM70 protein." in: Mitochondrion, Vol. 15, pp. 1-9, (2014) (PubMed).

Kov?ová, Mrá?ek, N?sková, Holzerová, Vrbacký, Pecina, Hejzlarová, K?u?ková, Rohlena, Neuzil, Houšt?k: "High molecular weight forms of mammalian respiratory chain complex II." in: PLoS ONE, Vol. 8, Issue 8, pp. e71869, (2013) (PubMed).

Burté, De Girolamo, Hargreaves, Billett: "Alterations in the mitochondrial proteome of neuroblastoma cells in response to complex 1 inhibition." in: Journal of proteome research, Vol. 10, Issue 4, pp. 1974-86, (2011) (PubMed).

Pollard, Spencer-Dene, Shukla, Howarth, Nye, El-Bahrawy, Deheragoda, Joannou, McDonald, Martin, Igarashi, Varsani-Brown, Rosewell, Poulsom, Maxwell, Stamp, Tomlinson: "Targeted inactivation of fh1 causes proliferative renal cyst development and activation of the hypoxia pathway." in: Cancer cell, Vol. 11, Issue 4, pp. 311-9, (2007) (PubMed).

Synonyme und alternative Namen zu FH

fumarate hydratase (FH), fumarate hydratase (fumH), fumarate hydratase (Fh), fumarate hydratase (fh), fumarate hydratase 1 (Fh1), DDBDRAFT_0205237, DDBDRAFT_0231397, DDBDRAFT_0231400, DDB_0205237, DDB_0231397, DDB_0231400, FH, Fh, Fh-1, Fh1, HLRCC, im:7152785, LRCC, MCL, MCUL1, ns:zf-e152, zf-e152, zgc:66253, zgc:77498

Bezeichner auf Proteinebene für FH

  • fumarate hydratase, mitochondrial
  • fumarate hydratase
  • fumarase
  • fumarate hydratase 1
  • EF-3
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