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Fibroblast Growth Factor Receptor Produkte

(Fibroblast Growth Factor Receptor (FGFR))
Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and normal skeletogenesis. Phosphorylates PLCG1, FRS2, GAB1 and SHB. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol- 1,4,5-trisphosphate. Phosphorylation of FRS2 triggers recruitment of GRB2, GAB1, PIK3R1 and SOS1, and mediates activation of RAS, MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Promotes phosphorylation of SHC1, STAT1 and PTPN11/SHP2. In the nucleus, enhances RPS6KA1 and CREB1 activity and contributes to the regulation of transcription. FGFR1 signaling is down-regulated by ubiquitination, internalization and degradation (By similarity).

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Ausgewählte Fibroblast Growth Factor Receptor Kategorien

Fibroblast Growth Factor Receptor Antikörper

High quality antibodies with extensive validation data.

Fibroblast Growth Factor Receptor ELISA Kits

Reliable ELISA kits for a wide range of species.

Empfohlene Fibroblast Growth Factor Receptor Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB
Validierungen
Kat. Nr. ABIN2267319
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB
Validierungen
Kat. Nr. ABIN2267321
Menge 1 mg
Datenblatt Datenblatt

Empfohlene Fibroblast Growth Factor Receptor ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN512888
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN626990
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Cow
Analytical Method Quantitative Competition ELISA
Validierungen
Kat. Nr. ABIN989385
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Fibroblast Growth Factor Receptor Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Sea Squirt
Source Yeast
Validierungen
Kat. Nr. ABIN1628579
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Hydra
Source Yeast
Validierungen
Kat. Nr. ABIN1623910
Menge 1 mg
Datenblatt Datenblatt

Synonyme und alternative Namen zu Fibroblast Growth Factor Receptor

heartless (htl), fibroblast growth factor receptor 1 L homeolog (fgfr1.L), fibroblast growth factor receptor (FGFR), fibroblast growth factor receptor 1 S homeolog (fgfr1.S), fibroblast growth factor receptor (fgfr), fibroblast growth factor receptor 1 (FGFR1), fibroblast growth factor receptor 1 (fgfr1), fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) L homeolog (fgfr3.L), basic fibroblast growth factor receptor 1 (CpipJ_CPIJ005849), ach, bfgfr, cd331, cd333, cek, cek2, CG7223, CT22273, CT39172, DFGF-R1, DFGF-R2, DFR-1, Dfr-1, DFR1, Dfr1, DFR1/DFGF-R2, Dmel\\CG7223, DmHD-38, DPR3, Dtk1, dtk1, DTRK(FR1), EMS2, FGF-R2, fgfbr, FGFR, fgfr, fgfr-1, fgfr-3, fgfr1, FGFR2, flg, FLG-1, flt-2, flt2, FR1, Fr1, hbgfr, HD-38, hsfgfr3ex, Htl, HTL/FGFR1, i79, i100, i150, j372, jtk4, kal2, n-sam, ogd, Tk1, x1fgfr, X1FGFR, XFGFR-1, xfgfr1, XFGFRA2

Bezeichner auf Proteinebene für Fibroblast Growth Factor Receptor

  • CG7223-PA
  • CG7223-PB
  • CG7223-PC
  • FGF receptor
  • fibroblast growth factor receptor
  • fibroblast growth factor receptor 1
  • htl-PA
  • htl-PB
  • htl-PC
  • FGFR-1
  • fibroblast growth factor receptor-1
  • fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome)
  • ibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome)
  • basic fibroblast growth factor receptor 1
  • basic fibroblast growth factor receptor 1-like
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