ABCB4 Antikörper (Center)

Produktnummer ABIN358591

Produktdetails anti-ABCB4 Antikörper

Target: ABCB4 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4))

Bindungsspezifität: Center

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABCB4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes ABCB4/MDR3 (Center)

Kreuzreaktivität (Details): Species reactivity (tested):Human and Mouse.

Aufreinigung: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the central region of human ABCB4.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blotting: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu ABCB4

Target: ABCB4 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4))

Andere Bezeichnung: ABCB4 / MDR3 (ABCB4 Produkte)

Synonyme: ABC21 antikoerper, GBD1 antikoerper, ICP3 antikoerper, MDR2 antikoerper, MDR2/3 antikoerper, MDR3 antikoerper, PFIC-3 antikoerper, PGY3 antikoerper, zgc:172149 antikoerper, Mdr2 antikoerper, Pgy-2 antikoerper, Pgy2 antikoerper, mdr-2 antikoerper, Pgy3 antikoerper, ABCB4a antikoerper, DEFB1 antikoerper, PGP2 antikoerper, PGY2 antikoerper, PGP3 antikoerper, ABCB4 antikoerper, RUNDC3B antikoerper, ATP binding cassette subfamily B member 4 antikoerper, ATP-binding cassette, sub-family B (MDR/TAP), member 4 antikoerper, beta-defensin 1-like antikoerper, ATP-binding cassette, sub-family B (MDR/TAP), member 1B antikoerper, RUN domain-containing protein 3B antikoerper, ABCB4 antikoerper, abcb4 antikoerper, Abcb4 antikoerper, LOC100861170 antikoerper, Abcb1b antikoerper, LOC101122517 antikoerper

Hintergrund: The membrane-associated protein encoded ABCB4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined, however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function.Synonyms: ATP-binding cassette sub-family B member 4, Multidrug resistance protein 3, P-glycoprotein 3, PGY3

Gen-ID: 5244, 9606

UniProt: P21439

Pathways: Regulation of Lipid Metabolism by PPARalpha