ABCB4 Antikörper (AA 624-654)

Produktnummer ABIN3030051

Produktdetails anti-ABCB4 Antikörper

Target: ABCB4 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4))

Bindungsspezifität: AA 624-654

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABCB4 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Aufreinigung: Purified

Immunogen: A portion of amino acids 624-654 from the human protein was used as the immunogen for this ABCB4 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the ABCB4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the ABCB4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu ABCB4

Target: ABCB4 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4))

Andere Bezeichnung: ABCB4 (ABCB4 Produkte)

Synonyme: ABC21 antikoerper, GBD1 antikoerper, ICP3 antikoerper, MDR2 antikoerper, MDR2/3 antikoerper, MDR3 antikoerper, PFIC-3 antikoerper, PGY3 antikoerper, zgc:172149 antikoerper, Mdr2 antikoerper, Pgy-2 antikoerper, Pgy2 antikoerper, mdr-2 antikoerper, Pgy3 antikoerper, ABCB4a antikoerper, DEFB1 antikoerper, PGP2 antikoerper, PGY2 antikoerper, PGP3 antikoerper, ABCB4 antikoerper, RUNDC3B antikoerper, ATP binding cassette subfamily B member 4 antikoerper, ATP-binding cassette, sub-family B (MDR/TAP), member 4 antikoerper, beta-defensin 1-like antikoerper, ATP-binding cassette, sub-family B (MDR/TAP), member 1B antikoerper, RUN domain-containing protein 3B antikoerper, ABCB4 antikoerper, abcb4 antikoerper, Abcb4 antikoerper, LOC100861170 antikoerper, Abcb1b antikoerper, LOC101122517 antikoerper

Hintergrund: The membrane-associated protein encoded ABCB4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined, however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function.

UniProt: P21439

Pathways: Regulation of Lipid Metabolism by PPARalpha