ABCB4 Antikörper (N-Term)
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- Target Alle ABCB4 Antikörper anzeigen
- ABCB4 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Pferd, Schaf, Schwein
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ABCB4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- AGAVAEEALG AIRTVIAFGG QNKELERYQK HLENAKEIGI KKAISANISM
- Homologie
- Cow: 86%, Dog: 77%, Guinea Pig: 77%, Horse: 77%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%, Sheep: 77%
- Produktmerkmale
- This is a rabbit polyclonal antibody against ABCB4. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human ABCB4
- Top Product
- Discover our top product ABCB4 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 1279 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- ABCB4 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4))
- Andere Bezeichnung
- ABCB4 (ABCB4 Produkte)
- Synonyme
- ABC21 antikoerper, GBD1 antikoerper, ICP3 antikoerper, MDR2 antikoerper, MDR2/3 antikoerper, MDR3 antikoerper, PFIC-3 antikoerper, PGY3 antikoerper, zgc:172149 antikoerper, Mdr2 antikoerper, Pgy-2 antikoerper, Pgy2 antikoerper, mdr-2 antikoerper, Pgy3 antikoerper, ABCB4a antikoerper, DEFB1 antikoerper, PGP2 antikoerper, PGY2 antikoerper, PGP3 antikoerper, ABCB4 antikoerper, RUNDC3B antikoerper, ATP binding cassette subfamily B member 4 antikoerper, ATP-binding cassette, sub-family B (MDR/TAP), member 4 antikoerper, beta-defensin 1-like antikoerper, ATP-binding cassette, sub-family B (MDR/TAP), member 1B antikoerper, RUN domain-containing protein 3B antikoerper, ABCB4 antikoerper, abcb4 antikoerper, Abcb4 antikoerper, LOC100861170 antikoerper, Abcb1b antikoerper, LOC101122517 antikoerper
- Hintergrund
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ABCB4, a membrane-associated protein, is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. ABCB4 is a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined, however, it may involve transport of phospholipids from liver hepatocytes into bile.The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined, however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function.
Alias Symbols: ABC21, GBD1, MDR2, MDR2/3, MDR3, PFIC-3, PGY3
Protein Interaction Partner: PIGY, TESK1, HAX1,
Protein Size: 1279 - Molekulargewicht
- 141 kDa
- Gen-ID
- 5244
- NCBI Accession
- NM_000443, NP_000434
- UniProt
- A4D1D4
- Pathways
- Regulation of Lipid Metabolism by PPARalpha
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