MALT1 Antikörper (C-Term)

Produktnummer ABIN3044126

Produktdetails anti-MALT1 Antikörper

Target: MALT1 (Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1))

Bindungsspezifität: AA 809-824, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MALT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Mucosa-associated lymphoid tissue lymphoma translocation protein 1(MALT1) detection. Tested with WB in Human.

Sequenz: DEIPFSFSDR LRISEK

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Mucosa-associated lymphoid tissue lymphoma translocation protein 1(MALT1) detection. Tested with WB in Human.
Gene Name: mucosa associated lymphoid tissue lymphoma translocation gene 1
Protein Name: Mucosa-associated lymphoid tissue lymphoma translocation protein 1

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human MALT1(809-824aa DEIPFSFSDRLRISEK).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for MALT1 is approximately 0.5 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu MALT1

Target: MALT1 (Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1))

Andere Bezeichnung: MALT1 (MALT1 Produkte)

Synonyme: malt1 antikoerper, MALT1 antikoerper, mlt antikoerper, mlt1 antikoerper, MLT antikoerper, MLT1 antikoerper, A630046N12 antikoerper, D430033E09Rik antikoerper, MALT paracaspase 2 antikoerper, MALT1 paracaspase antikoerper, MALT1 paracaspase S homeolog antikoerper, paracaspase 3 antikoerper, malt2 antikoerper, MALT1 antikoerper, malt1.S antikoerper, Malt1 antikoerper, PCASP3 antikoerper

Hintergrund: MALT1(Mucosa-associated lymphoid tissue lymphoma translocation protein 1), also called MLT or PARACASPASE, is a protein that in humans is encoded by the MALT1 gene. This gene has been found to be recurrently rearranged in chromosomal translocation with two other genes - baculoviral IAP repeat-containing protein 3(also known as apoptosis inhibitor 2) and immunoglobulin heavy chain locus - in mucosa-associated lymphoid tissue lymphomas. Dierlamm et al.(1999) and Akagi et al.(1999) mapped the MALT1 gene to chromosome 18q21. Using mouse models, Ruland et al.(2003) demonstrated that MALT1 is essential for T-cell activation, proliferation, and IL2 production in response to T-cell receptor ligation and strictly required for signal-specific NF-kappa-B(NFKB) activation induced by the T-cell receptor but not TNF-alpha or IL1 signaling. MALT1 operates downstream of BCL10, controls the catalytic activity of the canonical I-kappa-B kinase complex, and regulates the signaling of JNK and p38 MAP kinases.

Synonyms: Caspase like protein antibody|DKFZp434L132 antibody|MALT 1 antibody|MALT associated translocation antibody|MALT lymphoma associated translocation antibody|MALT lymphoma-associated translocation antibody|Malt1 antibody|MALT1_HUMAN antibody|MLT 1 antibody|MLT antibody|MLT1 antibody|Mucosa associated lymphoid tissue lymphoma translocation gene 1 antibody|Mucosa associated lymphoid tissue lymphoma translocation protein 1 antibody|Mucosa-associated lymphoid tissue lymphoma translocation protein 1 antibody|Paracaspase antibody

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteine