MALT1 Antikörper (AA 125-450)
Kurzübersicht für MALT1 Antikörper (AA 125-450) (ABIN3023032)
Target
Alle MALT1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 125-450
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Sequenz
- PGIKITVNPE SKAVLAGQFV KLCCRATGHP FVQYQWFKMN KEIPNGNTSE LIFNAVHVKD AGFYVCRVNN NFTFEFSQWS QLDVCDIPES FQRSVDGVSE SKLQICVEPT SQKLMPGSTL VLQCVAVGSP IPHYQWFKNE LPLTHETKKL YMVPYVDLEH QGTYWCHVYN DRDSQDSKKV EIIIDELNNL GHPDNKEQTT DQPLAKDKVA LLIGNMNYRE HPKLKAPLVD VYELTNLLRQ LDFKVVSLLD LTEYEMRNAV DEFLLLLDKG VYGLLYYAGH GYENFGNSFM VPVDAPNPYR SENCLCVQNI LKLMQEKETG LNVFLL
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 125-450 of human MALT1 (NP_776216.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid freeze / thaw cycles
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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: "miR-181d/MALT1 regulatory axis attenuates mesenchymal phenotype through NF-κB pathways in glioblastoma." in: Cancer letters, Vol. 396, pp. 1-9, (2017) (PubMed).
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- MALT1 (Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1))
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Andere Bezeichnung
- MALT1
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Hintergrund
- This gene has been found to be recurrently rearranged in chromosomal translocation with two other genes - baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) and immunoglobulin heavy chain locus - in mucosa-associated lymphoid tissue lymphomas. The protein encoded by this gene may play a role in NF-kappaB activation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.,MALT1,IMD12,MLT,MLT1,PCASP1,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Caspases,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,MALT1
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Molekulargewicht
- 91 kDa/92 kDa
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Gen-ID
- 10892
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UniProt
- Q9UDY8
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Pathways
- T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteine
Target
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