SDHB Antikörper (AA 42-59)

Produktnummer ABIN3032764

Produktdetails anti-SDHB Antikörper

Target: SDHB (Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB))

Bindungsspezifität: AA 42-59

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SDHB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity

Immunogen: Amino acids 42-59 (FAIYRWDPDKAGDKPHMQ-human) were used as the immunogen for this SDHB antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the SDHB antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the SDHB antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu SDHB

Target: SDHB (Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB))

Andere Bezeichnung: SDHB (SDHB Produkte)

Synonyme: succinate dehydrogenase 2-3 antikoerper, CG3283 antikoerper, Dmel\\CG3283 antikoerper, Ip antikoerper, SDH antikoerper, SDH-IP antikoerper, SDH-Ip antikoerper, SDHb antikoerper, sdhB antikoerper, CWS2 antikoerper, IP antikoerper, PGL4 antikoerper, SDH1 antikoerper, SDH2 antikoerper, SDHIP antikoerper, 0710008N11Rik antikoerper, fj46d06 antikoerper, wu:fj46d06 antikoerper, succinate dehydrogenase complex iron sulfur subunit B antikoerper, succinate dehydrogenase [ubiquinone] iron-sulfur subunit 3 antikoerper, Succinate dehydrogenase, subunit B (iron-sulfur) antikoerper, succinate dehydrogenase complex subunit B, iron sulfur (Ip) antikoerper, succinate dehydrogenase complex, subunit B, iron sulfur (Ip) antikoerper, succinate dehydrogenase complex subunit B, iron sulfur (Ip) S homeolog antikoerper, SDHB antikoerper, SDH2-3 antikoerper, SdhB antikoerper, sdhb antikoerper, Sdhb antikoerper, sdhb.S antikoerper

Hintergrund: Succinate Dehydrogenase Complex, Subunit B, iron sulfur protein is a protein that in humans is encoded by the SDHB gene. It is one of four protein subunits forming succinate dehydrogenase, the other three being SDHA, SDHC and SDHD. The SDHB subunit is connected to the SDHA subunit on the hydrophilic, catalytic end of the SDH complex. The entire SDHB transcript is encoded by 8 exons within approximately 40 kb by Au et al(1995). Pollard et al.(2005) stated that the nuclear-encoded Krebs cycle enzymes fumarate hydratase and succinate dehydrogenases like SDHB act as tumor suppressors, and germline mutations in these genes predispose individuals to leiomyomas and renal cancer and to paragangliomas, respectively. In affected members of families with paragangliomas-4, mutations were identified in the SDHB gene.

UniProt: P21912