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SDHB Antikörper (Middle Region)

SDHB Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Meerschweinchen, Rind (Kuh), Hund, Pferd, Kaninchen, Ziege, Saccharomyces cerevisiae WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2783181
  • Target Alle SDHB Antikörper anzeigen
    SDHB (Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB))
    Bindungsspezifität
    • 16
    • 11
    • 11
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 79
    • 32
    • 21
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte, Zebrafisch (Danio rerio), Meerschweinchen, Rind (Kuh), Hund, Pferd, Kaninchen, Ziege, Saccharomyces cerevisiae
    Wirt
    • 74
    • 5
    • 2
    Kaninchen
    Klonalität
    • 64
    • 17
    Polyklonal
    Konjugat
    • 40
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SDHB Antikörper ist unkonjugiert
    Applikation
    • 62
    • 27
    • 19
    • 13
    • 13
    • 11
    • 11
    • 5
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB)
    Sequenz
    YRWMIDSRDD FTEERLAKLQ DPFSLYRCHT IMNCTRTCPK GLNPGKAIAE
    Homologie
    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 79%, Zebrafish: 86%
    Produktmerkmale
    This is a rabbit polyclonal antibody against SDHB. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human SDHB
    Top Product
    Discover our top product SDHB Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 280 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Qattan, Radulovic, Crawford, Godovac-Zimmermann: "Spatial distribution of cellular function: the partitioning of proteins between mitochondria and the nucleus in MCF7 breast cancer cells." in: Journal of proteome research, Vol. 11, Issue 12, pp. 6080-101, (2012) (PubMed).

  • Target
    SDHB (Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB))
    Andere Bezeichnung
    SDHB (SDHB Produkte)
    Synonyme
    succinate dehydrogenase 2-3 antikoerper, CG3283 antikoerper, Dmel\\CG3283 antikoerper, Ip antikoerper, SDH antikoerper, SDH-IP antikoerper, SDH-Ip antikoerper, SDHb antikoerper, sdhB antikoerper, CWS2 antikoerper, IP antikoerper, PGL4 antikoerper, SDH1 antikoerper, SDH2 antikoerper, SDHIP antikoerper, 0710008N11Rik antikoerper, fj46d06 antikoerper, wu:fj46d06 antikoerper, succinate dehydrogenase complex iron sulfur subunit B antikoerper, succinate dehydrogenase [ubiquinone] iron-sulfur subunit 3 antikoerper, Succinate dehydrogenase, subunit B (iron-sulfur) antikoerper, succinate dehydrogenase complex subunit B, iron sulfur (Ip) antikoerper, succinate dehydrogenase complex, subunit B, iron sulfur (Ip) antikoerper, succinate dehydrogenase complex subunit B, iron sulfur (Ip) S homeolog antikoerper, SDHB antikoerper, SDH2-3 antikoerper, SdhB antikoerper, sdhb antikoerper, Sdhb antikoerper, sdhb.S antikoerper
    Hintergrund
    Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: IP, PGL4, SDH, SDH1, SDHIP, SDH2
    Protein Interaction Partner: UBC, XRN1, ITGA4, TP53BP1, HNRNPUL2, PIGS, TIMM50, MRPL45, SLC25A22, MRPL40, MRPS5, IWS1, MRPS10, MRPL20, OCIAD1, TOMM7, NDUFB11, LAMTOR2, TMED2, TOMM40, RBM14, IQGAP1, UQCRFS1, SSBP1, SDHA, OXA1L, NDUFV2, NDUFS1, NDUFB9, NDUFB6, NDUFA10, NDUFA9, GSN, ATP
    Protein Size: 280
    Molekulargewicht
    31 kDa
    Gen-ID
    6390
    NCBI Accession
    NM_003000, NP_002991
    UniProt
    P21912
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