SDHB Antikörper (AA 29-280)

Produktnummer ABIN5693211

Produktdetails anti-SDHB Antikörper

Target: SDHB (Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB))

Bindungsspezifität: AA 29-280

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SDHB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Marke: Picoband™

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for SDHB detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.

Immunogen: E. coli-derived human SDHB recombinant protein (Position: A29-V280).

Anwendungsinformationen

Applikationshinweise:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

Application Details: Western blot, 0.1-0.5 μg/mL
Immunohistochemistry(Paraffin-embedded Section), 0.5-1 μg/mL
Direct ELISA, 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Details zu SDHB

Target: SDHB (Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB))

Andere Bezeichnung: SDHB (SDHB Produkte)

Synonyme: succinate dehydrogenase 2-3 antikoerper, CG3283 antikoerper, Dmel\\CG3283 antikoerper, Ip antikoerper, SDH antikoerper, SDH-IP antikoerper, SDH-Ip antikoerper, SDHb antikoerper, sdhB antikoerper, CWS2 antikoerper, IP antikoerper, PGL4 antikoerper, SDH1 antikoerper, SDH2 antikoerper, SDHIP antikoerper, 0710008N11Rik antikoerper, fj46d06 antikoerper, wu:fj46d06 antikoerper, succinate dehydrogenase complex iron sulfur subunit B antikoerper, succinate dehydrogenase [ubiquinone] iron-sulfur subunit 3 antikoerper, Succinate dehydrogenase, subunit B (iron-sulfur) antikoerper, succinate dehydrogenase complex subunit B, iron sulfur (Ip) antikoerper, succinate dehydrogenase complex, subunit B, iron sulfur (Ip) antikoerper, succinate dehydrogenase complex subunit B, iron sulfur (Ip) S homeolog antikoerper, SDHB antikoerper, SDH2-3 antikoerper, SdhB antikoerper, sdhb antikoerper, Sdhb antikoerper, sdhb.S antikoerper

Hintergrund:

Synonyms: Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial, Iron-sulfur subunit of complex II, Ip, SDHB, SDH, SDH1

Background: SDHB(Succinate Dehydrogenase Complex, Subunit B, iron sulfur protein), also known as iron-sulfur subunit of complex II (Ip) or SDH2, HOMOLOG OF, is a protein that in humans is encoded by the SDHB gene. SDHB is one of four protein subunits forming succinate dehydrogenase, the other three being SDHA, SDHC and SDHD. The SDHB subunit is connected to the SDHA subunit on the hydrophilic, catalytic end of the SDH complex. The SDHB gene is mapped on 1p36.13. It is stated that the nuclear-encoded Krebs cycle enzymes fumarate hydratase and succinate dehydrogenases like SDHB act as tumor suppressors, and germline mutations in these genes predispose individuals to leiomyomas and renal cancer and to paragangliomas, respectively. In affected members of families with paragangliomas-4, mutations were identified in the SDHB gene.

UniProt: P21912