PKC epsilon Antikörper (AA 53-236)

Produktnummer ABIN3032377

Produktdetails anti-PKC epsilon Antikörper

Target: PKC epsilon (PRKCE) (Protein Kinase C, epsilon (PRKCE))

Bindungsspezifität: AA 53-236

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PKC epsilon Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity

Immunogen: Human partial recombinant protein (AA 53-236) was used as the immunogen for this PKC epsilon antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the PKC epsilon antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the PKC epsilon antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu PKC epsilon

Target: PKC epsilon (PRKCE) (Protein Kinase C, epsilon (PRKCE))

Andere Bezeichnung: PKC epsilon (PRKCE Produkte)

Synonyme: PKCE antikoerper, nPKC-epsilon antikoerper, 5830406C15Rik antikoerper, PKC[e] antikoerper, PKCepsilon antikoerper, Pkce antikoerper, R75156 antikoerper, fj59b07 antikoerper, prkce antikoerper, wu:fj59b07 antikoerper, pkce antikoerper, pkc-epsilon antikoerper, PRKCH antikoerper, protein kinase C epsilon antikoerper, protein kinase C, epsilon antikoerper, protein kinase C, epsilon a antikoerper, PRKCE antikoerper, Prkce antikoerper, prkcea antikoerper, prkce antikoerper

Hintergrund: Protein kinase C epsilon, also known as PKCE, is an enzyme that in humans is encoded by the PRKCE gene. It is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. It has been found that activation of PRKCE can induce < a href=../search_result.php?search_txt=trpv1>VR1 channel activity at room temperature in the absence of any other agonist. It plays a role in apoptosis signaling pathways in thyroid cells and it has been indicated that a naturally occurring PRKCE mutant that functions as a dominant negative can block cell death triggered by a variety of stimuli. Expression of PRKCE inhibits chemotherapy-induced caspase-3 activation and apoptosis, thereby leading to cell survival.

Gen-ID: 5581

Pathways: T-Zell Rezeptor Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Peptide Hormone Secretion, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling