PKC epsilon Antikörper (AA 213-243)

Produktnummer ABIN545461

Produktdetails anti-PKC epsilon Antikörper

Target: PKC epsilon (PRKCE) (Protein Kinase C, epsilon (PRKCE))

Bindungsspezifität: AA 213-243

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PKC epsilon Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit polyclonal antibody raised against synthetic peptide of PRKCE.

Kreuzreaktivität: Human

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to amino acids 213-243 at N-terminus of human PRKCE.

Anwendungsinformationen

Applikationshinweise: ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-PKC epsilon Antikörper (ABIN545461)

Tang, Bouyer, Mykoniatis, Buschmann, Matlin, Matthews: "Activated PKC{delta} and PKC{epsilon} inhibit epithelial chloride secretion response to cAMP via inducing internalization of the Na+-K+-2Cl- cotransporter NKCC1." in: The Journal of biological chemistry, Vol. 285, Issue 44, pp. 34072-85, (2010) (PubMed).

Gray, Zhou, Schafhalter-Zoppoth, Zhu, Mochly-Rosen, Messing: "Preservation of base-line hemodynamic function and loss of inducible cardioprotection in adult mice lacking protein kinase C epsilon." in: The Journal of biological chemistry, Vol. 279, Issue 5, pp. 3596-604, (2004) (PubMed).

Ling, Trollér, Zeidman, Lundberg, Larsson: "Induction of neurites by the regulatory domains of PKCdelta and epsilon is counteracted by PKC catalytic activity and by the RhoA pathway." in: Experimental cell research, Vol. 292, Issue 1, pp. 135-50, (2004) (PubMed).

McJilton, Van Sikes, Wescott, Wu, Foreman, Gregory, Weidner, Harris Ford, Morgan Lasater, Mohler, Terrian: "Protein kinase Cepsilon interacts with Bax and promotes survival of human prostate cancer cells." in: Oncogene, Vol. 22, Issue 39, pp. 7958-68, (2003) (PubMed).

Details zu PKC epsilon

Target: PKC epsilon (PRKCE) (Protein Kinase C, epsilon (PRKCE))

Andere Bezeichnung: PRKCE (PRKCE Produkte)

Synonyme: PKCE antikoerper, nPKC-epsilon antikoerper, 5830406C15Rik antikoerper, PKC[e] antikoerper, PKCepsilon antikoerper, Pkce antikoerper, R75156 antikoerper, fj59b07 antikoerper, prkce antikoerper, wu:fj59b07 antikoerper, pkce antikoerper, pkc-epsilon antikoerper, PRKCH antikoerper, protein kinase C epsilon antikoerper, protein kinase C, epsilon antikoerper, protein kinase C, epsilon a antikoerper, PRKCE antikoerper, Prkce antikoerper, prkcea antikoerper, prkce antikoerper

Gen-ID: 5581

Pathways: T-Zell Rezeptor Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Peptide Hormone Secretion, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling