CMA1 Antikörper (AA 22-247)

Produktnummer ABIN3030527

Produktdetails anti-CMA1 Antikörper

Target: CMA1 (Chymase 1, Mast Cell (CMA1))

Bindungsspezifität: AA 22-247

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CMA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity

Immunogen: Human partial recombinant protein (AA 22-247) was used as the immunogen for this Chymase antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the Chymase antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Chymase antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu CMA1

Target: CMA1 (Chymase 1, Mast Cell (CMA1))

Andere Bezeichnung: Chymase (CMA1 Produkte)

Synonyme: CYH antikoerper, MCT1 antikoerper, chymase antikoerper, MMCP-5 antikoerper, Mcp-5 antikoerper, Mcp5 antikoerper, Mcpt5 antikoerper, MCP3P antikoerper, CMA1 antikoerper, Chymase antikoerper, chymase 1 antikoerper, chymase 1, mast cell antikoerper, chymase-like antikoerper, CMA1 antikoerper, Cma1 antikoerper, LOC100008644 antikoerper

Hintergrund: Chymase is a major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1. Chymase is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, Chymase, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II.

Gen-ID: 1215

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis