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ATM Antikörper (AA 2870-3056)
ATM
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN3030031
Produktdetails anti-ATM Antikörper
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Target
Alle ATM Antikörper anzeigen
ATM
(Ataxia Telangiectasia Mutated (ATM))
Bindungsspezifität
Alle Epitope für ATM Antikörper
AA 2870-3056
Reaktivität
Alle Reaktivitäten für ATM Antikörper
Human
Wirt
Alle Wirte für ATM Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für ATM Antikörper
Polyklonal
Konjugat
Alle Konjugate für ATM Antikörper
Dieser ATM Antikörper ist unkonjugiert
Applikation
Alle Applikationen für ATM Antikörper
Western Blotting (WB)
Aufreinigung
Antigen affinity
Immunogen
Human partial recombinant protein (AA 2870-3056) was used as the immunogen for this ATM antibody.
Isotyp
IgG
Top Product
Discover our top product ATM Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Titration of the ATM antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Lagerung
-20 °C
Informationen zur Lagerung
The lyophilized ATM antibody can be stored at 4°C to -20°C. After reconstitution, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Details zu ATM
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Target
ATM
(Ataxia Telangiectasia Mutated (ATM))
Andere Bezeichnung
ATM (ATM Produkte )
Synonyme
ATM antikoerper, Atm antikoerper, CG6535 antikoerper, Dmel\\CG6535 antikoerper, Tefu antikoerper, atm antikoerper, atm/tefu antikoerper, dATM antikoerper, tef antikoerper, Xatm antikoerper, at1 antikoerper, atdc antikoerper, tel1 antikoerper, telo1 antikoerper, AT1 antikoerper, ATA antikoerper, ATC antikoerper, ATD antikoerper, ATDC antikoerper, ATE antikoerper, TEL1 antikoerper, TELO1 antikoerper, AI256621 antikoerper, C030026E19Rik antikoerper, telomere fusion antikoerper, ATM serine/threonine kinase L homeolog antikoerper, ATM serine/threonine kinase antikoerper, ataxia telangiectasia mutated antikoerper, ataxia telangiectasia mutated (atm) antikoerper, serine/threonine-protein kinase ATM antikoerper, tefu antikoerper, atm.L antikoerper, atm antikoerper, ATM antikoerper, EDI_100660 antikoerper, CpipJ_CPIJ001772 antikoerper, BDBG_08252 antikoerper, PAAG_02532 antikoerper, MCYG_05088 antikoerper, VDBG_06833 antikoerper, ACLA_015700 antikoerper, LOC5565620 antikoerper, MGYG_07634 antikoerper, PGTG_14279 antikoerper, Atm antikoerper
Hintergrund
Ataxia telangiectasia mutated, also known as TEL1 or TELO1, is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks. The ATM protein is a member of the phosphatidylinositol 3-kinase family of proteins that respond to DNA damage by phosphorylating key substrates involved in DNA repair and/or cell cycle control. The gene is mapped to chromosome 11q22.3. ATM has an essential role in the reconstitutive capacity of hematopoietic stem cells but is not as important for the proliferation or differentiation of progenitors in a telomere-independent manner. It functions directly in the repair of chromosomal DNA double-stranded breaks by maintaining DNA ends in repair complexes generated during lymphocyte gene assembly.
Gen-ID
472
Pathways
p53 Signalweg , Apoptose , DNA Reparatur , Inositol Metabolic Process , Positive Regulation of Response to DNA Damage Stimulus
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