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TNFAIP3 Antikörper (AA 1-190)
TNFAIP3
Reaktivität: Human
WB, IHC
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN6219332
Produktdetails anti-TNFAIP3 Antikörper
(ausblenden)
Target
Alle TNFAIP3 Antikörper anzeigen
TNFAIP3
(Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3))
Bindungsspezifität
Alle Epitope für TNFAIP3 Antikörper
AA 1-190
Reaktivität
Alle Reaktivitäten für TNFAIP3 Antikörper
Human
Wirt
Alle Wirte für TNFAIP3 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für TNFAIP3 Antikörper
Polyklonal
Konjugat
Alle Konjugate für TNFAIP3 Antikörper
Dieser TNFAIP3 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für TNFAIP3 Antikörper
Western Blotting (WB), Immunohistochemistry (IHC)
Sequenz
MAEQVLPQAL YLSNMRKAVK IRERTPEDIF KPTNGIIHHF KTMHRYTLEM FRTCQFCPQF REIIHKALID RNIQATLESQ KKLNWCREVR KLVALKTNGD GNCLMHATSQ YMWGVQDTDL VLRKALFSTL KETDTRNFKF RWQLESLKSQ EFVETGLCYD TRNWNDEWDN LIKMASTDTP MARSGLQYNS
Kreuzreaktivität
Human, Maus, Ratte
Produktmerkmale
Polyclonal Antibodies
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human TNFAIP3 (NP_006281.1).
Isotyp
IgG
Alternativen
(anzeigen)
Anwendungsinformationen
(ausblenden)
Applikationshinweise
WB,1:500 - 1:2000,IHC,1:50 - 1:200
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
(ausblenden)
Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid freeze / thaw cycles
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Referenzen für anti-TNFAIP3 Antikörper (ABIN6219332)
(ausblenden)
He, Ma, Tian, Wei, Zhu, Li, Zhang, Wang, Zhang, Zhong : "ERRα negatively regulates type I interferon induction by inhibiting TBK1-IRF3 interaction. " in: PLoS pathogens , Vol. 13 , Issue 6 , pp. e1006347 , (2017 ) (PubMed ).
Details zu TNFAIP3
(ausblenden)
Target
TNFAIP3
(Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3))
Andere Bezeichnung
TNFAIP3 (TNFAIP3 Produkte )
Synonyme
tnfaip3 antikoerper, MGC82339 antikoerper, TNFAIP3 antikoerper, A20 antikoerper, OTUD7C antikoerper, TNFA1P2 antikoerper, Tnfip3 antikoerper, TNF alpha induced protein 3 antikoerper, TNF alpha induced protein 3 S homeolog antikoerper, tumor necrosis factor, alpha-induced protein 3 antikoerper, TNFAIP3 antikoerper, tnfaip3.S antikoerper, Tnfaip3 antikoerper
Hintergrund
This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene.,A20,AISBL,OTUD7C,TNFA1P2,TNFAIP3,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Inhibition of Apoptosis,Growth factor,TNF,Ubiquitin,Immunology & Inflammation,Cytokines,TNF,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TNFAIP3
Molekulargewicht
89 kDa
Gen-ID
7128
UniProt
P21580
Pathways
TLR Signalweg , Activation of Innate immune Response , Cellular Response to Molecule of Bacterial Origin , Production of Molecular Mediator of Immune Response
Zuletzt angesehen
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