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Retinoblastoma 1 Antikörper (pSer780)

Name: Retinoblastoma 1 Antikörper (pSer780)
Brand: antibodies-online
SKU: ABIN3020472
Price: 849.42 EUR
Availability: InStock

RB1 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated

Western blot analysis of extracts from 3T3 cells, using Phospho-RB1-S780 antibody. (Retinoblastoma 1 Antikörper (pSer780))

Immunohistochemistry of paraffin-embedded rat brain using Phospho-RB-S780 Rabbit pAb (ABIN3020471, ABIN3020472, ABIN3020473 and ABIN1681996) at dilution of 1:100 (40x lens). (Retinoblastoma 1 Antikörper (pSer780))

IHC

Immunohistochemistry (IHC) image for anti-Retinoblastoma 1 (RB1) (pSer780) antibody (ABIN3020472) (Retinoblastoma 1 Antikörper (pSer780))

IHC

Immunofluorescence staining of methanol-fixed Hela cells, using Phospho-RB1-S780 antibody. (Retinoblastoma 1 Antikörper (pSer780))

Western blot analysis of extracts of NIH/3T3 cells, using Phospho-RB-S780 antibody (ABIN3020471, ABIN3020472, ABIN3020473 and ABIN1681996) at dilution. (Retinoblastoma 1 Antikörper (pSer780))

Immunohistochemistry of paraffin-embedded mouse brain using Phospho-RB-S780 Rabbit pAb (ABIN3020471, ABIN3020472, ABIN3020473 and ABIN1681996) at dilution of 1:100 (40x lens). (Retinoblastoma 1 Antikörper (pSer780))

IHC

Immunohistochemistry of paraffin-embedded human colon using Phospho-RB-S780 Rabbit pAb (ABIN3020471, ABIN3020472, ABIN3020473 and ABIN1681996) at dilution of 1:100 (40x lens). (Retinoblastoma 1 Antikörper (pSer780))

IHC

7 Abbildungen

Produktnummer ABIN3020472

Datenblatt (PDF)

Target Alle Retinoblastoma 1 (RB1) Antikörper anzeigen

Retinoblastoma 1 (RB1)
Bindungsspezifität
36

34

29

25

24

22

20

15

11

10

10

7

6

6

4

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer780
Reaktivität
301

120

101

6

4

4

4

3

3

3

2

1

1

1
Human
Wirt
252

52
Kaninchen
Passende Sekundärantikörper
Klonalität
238

66
Polyklonal
Konjugat
153

19

17

16

11

11

8

8

6

6

6

6

6

6

6

6

6

1

1

1

1

1

1

1
Dieser Retinoblastoma 1 Antikörper ist unkonjugiert
Applikation
227

132

114

80

79

42

42

36

28

20

19

9

8

6

6

6

4

2

1
Western Blotting (WB), Immunohistochemistry (IHC)

Kreuzreaktivität

Human, Maus, Ratte

Produktmerkmale

Phosphorylated Antibodies

Immunogen

A phospho specific peptide corresponding to residues surrounding S780 of human RB

Isotyp

IgG

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RB1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Retinoblastoma 1 (RB1) (pSer780) antibody
RB1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen

Nur für Forschungszwecke einsetzbar
Buffer

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20°C. Avoid freeze / thaw cycles.
Target

Retinoblastoma 1 (RB1)

Andere Bezeichnung

RB1 (RB1 Produkte)

Synonyme

OSRC antikoerper, RB antikoerper, p105-Rb antikoerper, pRb antikoerper, pp110 antikoerper, Rb antikoerper, Rb-1 antikoerper, P105-RB antikoerper, PP110 antikoerper, RB11 antikoerper, zgc:154147 antikoerper, RB transcriptional corepressor 1 antikoerper, RB transcriptional corepressor like 1 antikoerper, retinoblastoma 1 antikoerper, RB1 antikoerper, RBL1 antikoerper, Rb1 antikoerper, rb1 antikoerper

Hintergrund

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.,OSRC,PPP1R130,RB,p105-Rb,pRb,pp110,RB1,Rb,Epigenetics & Nuclear Signaling,Transcription Factors,DNA Damage & Repair,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,G1/S Checkpoint,Protein phosphorylation,RB1

Molekulargewicht

106 kDa

Gen-ID

5925

UniProt

P06400

Pathways

Zellzyklus, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagie