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Retinoblastoma 1 Produkte

(Retinoblastoma 1 (RB1))
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008].

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Ausgewählte Retinoblastoma 1 Kategorien

Retinoblastoma 1 Antikörper

High quality antibodies with extensive validation data.

Retinoblastoma 1 ELISA Kits

Reliable ELISA kits for a wide range of species.

Retinoblastoma 1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Retinoblastoma 1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Rat
Applikation WB, ELISA, IHC (p), IF (cc), IF (p), FACS, IHC (fro)
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN675294
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validierungen
  • (1)
Kat. Nr. ABIN712946
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC (p), FACS
Validierungen
  • (4)
Kat. Nr. ABIN652516
Menge 400 μL
Datenblatt Datenblatt

Empfohlene Retinoblastoma 1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (5)
Kat. Nr. ABIN6574260
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validierungen
  • (3)
Kat. Nr. ABIN5526749
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6969918
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Retinoblastoma 1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1317543
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3094954
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3132938
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Retinoblastoma 1 Produkten

Ma, Jiang, Zhang, Ding, Xu, Lu: "IGFBP-rP1 acts as a potential tumor suppressor via the suppression of ERK signaling pathway in endometrial cancer cells." in: Molecular medicine reports, Vol. 16, Issue 2, pp. 1445-1450, (2018) (PubMed).

Béguelin, Rivas, Calvo Fernández, Teater, Purwada, Redmond, Shen, Challman, Elemento, Singh, Melnick: "EZH2 enables germinal centre formation through epigenetic silencing of CDKN1A and an Rb-E2F1 feedback loop." in: Nature communications, Vol. 8, Issue 1, pp. 877, (2018) (PubMed).

Huang, Xu, Zhang, Ma, Guo, Wang, Zhang, Gou, Chen, Liang, Cao: "ICAM-1-Targeted Liposomes Loaded with Liver X Receptor Agonists Suppress PDGF-Induced Proliferation of Vascular Smooth Muscle Cells." in: Nanoscale research letters, Vol. 12, Issue 1, pp. 322, (2017) (PubMed).

Qin, Zheng, Zhou, Ou, Huang, Yan, Qin, Yang, Su, Bai, Guo, Lin: "Tsc1 deficiency impairs mammary development in mice by suppression of AKT, nuclear ERα, and cell-cycle-driving proteins." in: Scientific reports, Vol. 6, pp. 19587, (2017) (PubMed).

Wu, Fu, Liu, Li, Huang, Xue, Xu, Sun, Zhao, Mi: "Cell proliferation downregulated by TGF-β2-triggered G1/S checkpoint in clinical CAFs." in: Cell cycle (Georgetown, Tex.), Vol. 16, Issue 2, pp. 172-178, (2017) (PubMed).

Tan, Wu, Ren, Wang, Li, Alshenawy, Li, Cui, Luo, Siegel, Fu, Lu: "A Point Mutation in DNA Polymerase β (POLB) Gene Is Associated with Increased Progesterone Receptor (PR) Expression and Intraperitoneal Metastasis in Gastric Cancer." in: Journal of Cancer, Vol. 7, Issue 11, pp. 1472-80, (2016) (PubMed).

Jie, Weilong, Ming, Fei, Xinghua, Junhua, Guobin, Kaixiong, Xiaoming: "Enhancer of zeste homolog 2 depletion induces cellular senescence via histone demethylation along the INK4/ARF locus." in: The international journal of biochemistry & cell biology, Vol. 65, pp. 104-12, (2016) (PubMed).

Zhang, Sun, Ye, Ashraf, Chen, Zhu, He, Xu, Wei, Chen, Fu, Liu, Cao: "Quantitative Label-Free Phosphoproteomics Reveals Differentially Regulated Protein Phosphorylation Involved in West Nile Virus-Induced Host Inflammatory Response." in: Journal of proteome research, Vol. 14, Issue 12, pp. 5157-68, (2016) (PubMed).

Iwahori, Hakki, Chou, Kalejta: "Molecular Determinants for the Inactivation of the Retinoblastoma Tumor Suppressor by the Viral Cyclin-dependent Kinase UL97." in: The Journal of biological chemistry, Vol. 290, Issue 32, pp. 19666-80, (2015) (PubMed).

Wu, Lv, He, Zhang, Mei, Cui, Huang, Xie, Xu, Zhang: "MicroRNA-188 suppresses G1/S transition by targeting multiple cyclin/CDK complexes." in: Cell communication and signaling : CCS, Vol. 12, pp. 66, (2015) (PubMed).

Synonyme und alternative Namen zu Retinoblastoma 1

RB transcriptional corepressor 1 (RB1), RB transcriptional corepressor like 1 (RBL1), RB transcriptional corepressor 1 (Rb1), RB transcriptional corepressor 1 (rb1), retinoblastoma 1 (rb1), OSRC, p105-Rb, P105-RB, pp110, PP110, pRb, RB, Rb, Rb-1, RB11, zgc:154147

Bezeichner auf Proteinebene für Retinoblastoma 1

  • retinoblastoma suspectibility protein
  • retinoblastoma-associated protein
  • retinoblastoma-like protein 1
  • pp105
  • Retinoblastoma 1 (including osteosarcoma)
  • pRb
  • rb
  • retinoblastoma 1 (including osteosarcoma)
  • retinoblastoma protein
  • retinoblastoma, susceptibility
  • Retinoblastoma-associated protein
  • retinoblastoma 1
  • retinoblastoma-associated protein-like
  • spc
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