EIF2AK2 Antikörper (pThr451)

Produktnummer ABIN2964740

Produktdetails anti-EIF2AK2 Antikörper

Target: EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))

Bindungsspezifität: pThr451

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF2AK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Spezifität: Phosphorylation site-specific antibody selective for the phosphorylated form of the PKR (double-stranded RNA-dependent protein kinase) protein containing a phosphate on threonine451. Recognizes a protein of 65-68kD resolved by SDS-PAGE, identified as PKR. Species cross-reactivity: Human and mouse (73 % homologous).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic phosphopeptide derived from the region of PKR that contains threonine451. The sequence was aligned to human.

Type of Immunogen: Synthetic phospho-peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Approved: IHC, WB (1:1000)

Usage: Suitable for use in Western Blot and Immunohistochemistry. Western Blot: 1:1000. Positive control: HeLa cells stimulated with interferon gamma (IFN ) and calyculin.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Dulbecco's PBS (without Mg2+, Ca2+),  pH 7.3, 50 % glycerol, 1 mg/mL BSA (IgG, protease free), 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Details zu EIF2AK2

Target: EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))

Andere Bezeichnung: EIF2AK2 / PKR (EIF2AK2 Produkte)

Synonyme: PKR antikoerper, pkr antikoerper, EIF2AK2 antikoerper, DKFZp469K1934 antikoerper, EIF2AK1 antikoerper, PRKR antikoerper, 2310047A08Rik antikoerper, 4732414G15Rik antikoerper, AI467567 antikoerper, AI747578 antikoerper, Pkr antikoerper, Prkr antikoerper, Tik antikoerper, eukaryotic translation initiation factor 2 alpha kinase 2 antikoerper, eukaryotic translation initiation factor 2-alpha kinase 2 antikoerper, EIF2AK2 antikoerper, eif2ak2 antikoerper, Eif2ak2 antikoerper

Hintergrund: Name/Gene ID: EIF2AK2
Subfamily: Translational Control Kinase
Family: Protein Kinase

Synonyms: EIF2AK2, p1/eIF-2A protein kinase, p68 kinase, PRKR, EIF-2A protein kinase 2, p68, Protein kinase RNA-activated, Tik

Gen-ID: 5610

UniProt: P19525

Pathways: DNA Reparatur, ER-Nucleus Signaling, Hepatitis C