EIF2AK2 Antikörper (AA 1-100)
Kurzübersicht für EIF2AK2 Antikörper (AA 1-100) (ABIN519273)
Target
Alle EIF2AK2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1-100
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Verwendungszweck
- Mouse monoclonal antibody raised against a partial recombinant EIF2AK2.
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Sequenz
- MAGDLSAGFF MEELNTYRQK QGVVLKYQEL PNSGPPHDRR FTFQVIIDGR EFPEGEGRSK KEAKNAAAKL AVEILNKEKK AVSPLLLTTT NSSEGLSMGN
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Kreuzreaktivität
- Human
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Produktmerkmale
- Antibody Reactive Against Recombinant Protein.
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Immunogen
- EIF2AK2 (NP_002750, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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Isotyp
- IgG1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- In 1x PBS, pH 7.4
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Handhabung
- Aliquot to avoid repeated freezing and thawing.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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: "PKR regulates proliferation, differentiation, and survival of murine hematopoietic stem/progenitor cells." in: Blood, Vol. 121, Issue 17, pp. 3364-74, (2013) (PubMed).
: "PKR negatively regulates leukemia progression in association with PP2A activation, Bcl-2 inhibition and increased apoptosis." in: Blood cancer journal, Vol. 3, pp. e144, (2013) (PubMed).
: "Increased expression of the dsRNA-activated protein kinase PKR in breast cancer promotes sensitivity to doxorubicin." in: PLoS ONE, Vol. 7, Issue 9, pp. e46040, (2012) (PubMed).
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- EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))
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Andere Bezeichnung
- EIF2AK2
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Hintergrund
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Full Gene Name: eukaryotic translation initiation factor 2-alpha kinase 2
Synonyms: EIF2AK1,MGC126524,PKR,PRKR -
Gen-ID
- 5610
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NCBI Accession
- NM_002759
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Pathways
- DNA Reparatur, ER-Nucleus Signaling, Hepatitis C
Target
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