E2F1 Antikörper (C-Term)
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- Target Alle E2F1 Antikörper anzeigen
- E2F1 (E2F Transcription Factor 1 (E2F1))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte, Hund, Meerschweinchen, Kaninchen, Pferd
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser E2F1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- REDFSGLLPE EFISLSPPHE ALDYHFGLEE GEGIRDLFDC DFGDLTPLDF
- Homologie
- Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against E2F1. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human E2F1
- Top Product
- Discover our top product E2F1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 437 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- E2F1 (E2F Transcription Factor 1 (E2F1))
- Andere Bezeichnung
- E2F1 (E2F1 Produkte)
- Synonyme
- CG6376 antikoerper, DRTF1/E2F antikoerper, DmE2F-1 antikoerper, Dmel\\CG6376 antikoerper, Dp antikoerper, E(Sev-CycE)3A antikoerper, E(var)3-93E antikoerper, E(var)3-95E antikoerper, E(var)93E antikoerper, E2F antikoerper, E2F-1 antikoerper, E2F1 antikoerper, E2f1 antikoerper, Evar(3)164 antikoerper, dE2F antikoerper, dE2F1 antikoerper, dE2f antikoerper, dE2f1 antikoerper, de2f1 antikoerper, def21 antikoerper, drosE2F1 antikoerper, e2f antikoerper, e2f1 antikoerper, l(3)07172 antikoerper, l(3)j3B1 antikoerper, l(3)j3C2 antikoerper, l(3)rM729 antikoerper, RBAP1 antikoerper, RBBP3 antikoerper, RBP3 antikoerper, mKIAA4009 antikoerper, xE2F antikoerper, ATE2FB antikoerper, E2F TRANSCRIPTION FACTOR-1 E2F1 antikoerper, E2F transcription factor 1 antikoerper, E2FB antikoerper, E2FB TRANSCRIPTION FACTOR antikoerper, E2F transcription factor 1 antikoerper, E2F transcription factor 1 L homeolog antikoerper, E2f1 antikoerper, E2F1 antikoerper, e2f1.L antikoerper
- Hintergrund
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The protein encoded by E2F1 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis.
Alias Symbols: RBP3, E2F-1, RBAP1, RBBP3
Protein Interaction Partner: RB1, SIRT1, KDM2A, LAMTOR5, EP300, KAT2B, VHL, RARA, STAT1, NCOR2, STOML1, RBL1, MAGEA11, SKP2, UHRF2, UBC, GTF2H1, ERCC3, SPT15, TFB1, TBP, NCOA3, CEBPE, PARP1, PRMT2, RBL2, CCNE1, TFDP2, TFDP1, CDKN2A, CEBPD, CDK2, CDK1, NEDD8, MCPH1, DDB2, DDB1, XIAP,
Protein Size: 437 - Molekulargewicht
- 47 kDa
- Gen-ID
- 1869
- NCBI Accession
- NM_005225, NP_005216
- UniProt
- Q01094
- Pathways
- p53 Signalweg, Zellzyklus, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Autophagie
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