TIGIT Antikörper (C-Term)

Produktnummer ABIN2790450

Produktdetails anti-TIGIT Antikörper

Target: TIGIT (T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TIGIT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ALRIHSVEGD LRRKSAGQEE WSPSAPSPPG SCVQAEAAPA GLCGEQRGED

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TIGIT. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human TIGIT

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 244 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TIGIT

Target: TIGIT (T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT))

Andere Bezeichnung: TIGIT (TIGIT Produkte)

Synonyme: VSIG9 antikoerper, VSTM3 antikoerper, WUCAM antikoerper, ENSMUSG00000071552 antikoerper, Vstm3 antikoerper, RGD1563191 antikoerper, T-cell immunoreceptor with Ig and ITIM domains antikoerper, T cell immunoreceptor with Ig and ITIM domains antikoerper, TIGIT antikoerper, Tigit antikoerper

Hintergrund: This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity, this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.
Alias Symbols: DKFZp667A205, FLJ39873, VSIG9, VSTM3, WUCAM
Protein Interaction Partner: PVRL4, PVRL3, PVRL2, PVR,
Protein Size: 244

Molekulargewicht: 26 kDa

Gen-ID: 201633

NCBI Accession: NM_173799, NP_776160

UniProt: Q495A1

Pathways: Cancer Immune Checkpoints