PIK3C2A Antikörper (C-Term)

Produktnummer ABIN2498949

Produktdetails anti-PIK3C2A Antikörper

Target: PIK3C2A (Phosphoinositide-3-Kinase, Class 2, alpha Polypeptide (PIK3C2A))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Schwein, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIK3C2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PNPYVKTYLL PDNHKTSKRK TKISRKTRNP TFNEMLVYSG YSKETLRQRE

Homologie: Dog: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against PIK3C2A. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human PIK3C2A

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PIK3C2A

Target: PIK3C2A (Phosphoinositide-3-Kinase, Class 2, alpha Polypeptide (PIK3C2A))

Andere Bezeichnung: PIK3C2A (PIK3C2A Produkte)

Synonyme: CPK antikoerper, PI3-K-C2(ALPHA) antikoerper, PI3-K-C2A antikoerper, cpk antikoerper, pi3-k-c2a antikoerper, Cpk-m antikoerper, PI3KC2 antikoerper, sb:cb156 antikoerper, si:dkey-24l11.7 antikoerper, wu:fc02a04 antikoerper, phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha antikoerper, phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha antikoerper, phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha S homeolog antikoerper, phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha antikoerper, PIK3C2A antikoerper, Pik3c2a antikoerper, pik3c2a antikoerper, pik3c2a.S antikoerper, LOC100548137 antikoerper

Hintergrund: The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling.
Alias Symbols: CPK, PI3-K-C2A, PI3-K-C2(ALPHA)
Protein Size: 1306

Molekulargewicht: 143 kDa

Gen-ID: 5286

NCBI Accession: NM_002645, NP_002636

UniProt: O00443

Pathways: EGFR Signaling Pathway, Inositol Metabolic Process, Platelet-derived growth Factor Receptor Signaling