PIK3C2A Antikörper (C-Term)

Produktnummer ABIN5534605

Produktdetails anti-PIK3C2A Antikörper

Target: PIK3C2A (Phosphoinositide-3-Kinase, Class 2, alpha Polypeptide (PIK3C2A))

Bindungsspezifität: AA 1431-1458, C-Term

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIK3C2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PIK3C2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1431-1458 amino acids from the C-terminal region of human PIK3C2A.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu PIK3C2A

Target: PIK3C2A (Phosphoinositide-3-Kinase, Class 2, alpha Polypeptide (PIK3C2A))

Andere Bezeichnung: PIK3C2A (PIK3C2A Produkte)

Synonyme: CPK antikoerper, PI3-K-C2(ALPHA) antikoerper, PI3-K-C2A antikoerper, cpk antikoerper, pi3-k-c2a antikoerper, Cpk-m antikoerper, PI3KC2 antikoerper, sb:cb156 antikoerper, si:dkey-24l11.7 antikoerper, wu:fc02a04 antikoerper, phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha antikoerper, phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha antikoerper, phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha S homeolog antikoerper, phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha antikoerper, PIK3C2A antikoerper, Pik3c2a antikoerper, pik3c2a antikoerper, pik3c2a.S antikoerper, LOC100548137 antikoerper

Hintergrund: The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling.

Molekulargewicht: 191 kDa

Gen-ID: 5286

UniProt: O00443

Pathways: EGFR Signaling Pathway, Inositol Metabolic Process, Platelet-derived growth Factor Receptor Signaling