PIK3C2A Produkte
(Phosphoinositide-3-Kinase, Class 2, alpha Polypeptide (PIK3C2A))
Kategorien
The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling. [provided by RefSeq, Jul 2008].
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Ausgewählte PIK3C2A Kategorien
PIK3C2A Antikörper
High quality antibodies with extensive validation data.
PIK3C2A ELISA Kits
Reliable ELISA kits for a wide range of species.
PIK3C2A Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PIK3C2A Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (4)
Kat. Nr.
ABIN7431707
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC (p), IF
Validierungen
- (4)
Kat. Nr.
ABIN518885
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
IHC, ELISA
Validierungen
- (3)
Kat. Nr.
ABIN185194
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene PIK3C2A ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6958551
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (2)
Kat. Nr.
ABIN1116456
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN2851450
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PIK3C2A Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1315063
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
Kat. Nr.
ABIN5509086
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7410745
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PIK3C2A Produkten
: "Mitotic Spindle Assembly and Genomic Stability in Breast Cancer Require PI3K-C2α Scaffolding Function. ..." in: Cancer cell, Vol. 32, Issue 4, pp. 444-459.e7, (2017) (PubMed).: "miR-218 opposes a critical RTK-HIF pathway in mesenchymal glioblastoma." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 1, pp. 291-6, (2014) (PubMed).
: "PI3K/AKT pathway mediates induction of IL-1RA by TSH in fibrocytes: modulation by PTEN." in: The Journal of clinical endocrinology and metabolism, Vol. 99, Issue 9, pp. 3363-72, (2014) (PubMed).
: "The SH3 domain of postsynaptic density 95 mediates inflammatory pain through phosphatidylinositol-3-kinase recruitment." in: EMBO reports, Vol. 11, Issue 6, pp. 473-8, (2010) (PubMed).
: "Phosphoinositide 3-kinase C2alpha is activated upon smooth muscle cell migration and regulated by alpha(v)beta(3) integrin engagement." in: Biochemical and biophysical research communications, Vol. 297, Issue 2, pp. 261-6, (2002) (PubMed).
: "The class II phosphoinositide 3-kinase PI3K-C2alpha is concentrated in the trans-Golgi network and present in clathrin-coated vesicles." in: The Journal of biological chemistry, Vol. 275, Issue 16, pp. 11943-50, (2000) (PubMed).
: "Cpk is a novel class of Drosophila PtdIns 3-kinase containing a C2 domain." in: The Journal of biological chemistry, Vol. 271, Issue 23, pp. 13892-9, (1996) (PubMed).
Synonyme und alternative Namen zu PIK3C2A
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha (PIK3C2A), phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha (Pik3c2a), phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha (pik3c2a), phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha S homeolog (pik3c2a.S), phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (LOC100548137), phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha (Pik3c2a), phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha (pik3c2a), CPK, cpk, Cpk-m, PI3-K-C2(ALPHA), PI3-K-C2A, pi3-k-c2a, PI3KC2, sb:cb156, si:dkey-24l11.7, wu:fc02a04Bezeichner auf Proteinebene für PIK3C2A
- C2-containing phosphatidylinositol kinase
- PI3K-C2-alpha
- PI3K-C2alpha
- phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha
- phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit alpha
- phosphoinositide 3-kinase-C2-alpha
- phosphoinositide-3-kinase, class 2, alpha polypeptide
- ptdIns-3-kinase C2 subunit alpha
- phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide
- phosphoinositide-3-kinase, class 2 alpha polypeptide
- pi3-k-c2(alpha)
- Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide
- p170
- LOW QUALITY PROTEIN: phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha
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