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PIM1 Produkte

(Pim-1 Oncogene (PIM1))
The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011].

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Ausgewählte PIM1 Kategorien

PIM1 Antikörper

High quality antibodies with extensive validation data.

PIM1 ELISA Kits

Reliable ELISA kits for a wide range of species.

PIM1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PIM1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Applikation WB, IHC, IP, ICC
Validierungen
  • (4)
Kat. Nr. ABIN7429160
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF
Validierungen
  • (4)
Kat. Nr. ABIN562235
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC
Validierungen
  • (4)
Kat. Nr. ABIN7269375
Menge 100 μL
Datenblatt Datenblatt

Empfohlene PIM1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6958588
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN1380319
Menge 2 x 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Competition ELISA
Validierungen
Kat. Nr. ABIN1503732
Menge 96 tests
Datenblatt Datenblatt

Empfohlene PIM1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7124452
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1315100
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1315102
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PIM1 Produkten

Xu, Xiong, Cao, Huang, Wang, You, Zhou, Zheng, Hu, Zhang, Zhao: "PIM-1 contributes to the malignancy of pancreatic cancer and displays diagnostic and prognostic value." in: Journal of experimental & clinical cancer research : CR, Vol. 35, Issue 1, pp. 133, (2017) (PubMed).

Albertson, Schmidt, Bearss, Tripp, Bearss, Liu: "Patterns and Significance of PIM Kinases in Urothelial Carcinoma." in: Applied immunohistochemistry & molecular morphology : AIMM, Vol. 23, Issue 10, pp. 717-23, (2016) (PubMed).

Wu, Lu, He, Jin: "PIM1 polymorphism and PIM1 expression as predisposing factors of esophageal squamous cell carcinoma in the Asian population." in: OncoTargets and therapy, Vol. 9, pp. 2919-25, (2016) (PubMed).

Plum, Warnecke-Eberz, Dhaouadi, Alakus, Drebber, Metzger, Prenzel, Hölscher, Bollschweiler: "Molecular markers predicting lymph node metastasis in early esophageal cancer." in: Histology and histopathology, pp. 11618, (2015) (PubMed).

Herzog, Fink, Weitmann, Friedel, Hadlich, Langner, Kindermann, Holm, Böhm, Eskilsson, Miletic, Hildner, Fritsch, Vogelgesang, Havemann, Ritter, Meyer zu Schwabedissen, Rauch, Hoffmann, Kroemer et al.: "Pim1 kinase is upregulated in glioblastoma multiforme and mediates tumor cell survival. ..." in: Neuro-oncology, Vol. 17, Issue 2, pp. 223-42, (2015) (PubMed).

Egli, Zajonz, Burger, Schweighoffer: "Human CD180 Transmits Signals via the PIM-1L Kinase." in: PLoS ONE, Vol. 10, Issue 11, pp. e0142741, (2015) (PubMed).

Menter, Ernst, Drachneris, Dirnhofer, Barghorn, Went, Tzankov: "Phenotype profiling of primary testicular diffuse large B-cell lymphomas." in: Hematological oncology, Vol. 32, Issue 2, pp. 72-81, (2014) (PubMed).

Renard, Paulin, Breuils-Bonnet, Simard, Pibarot, Bonnet, Provencher: "Pim-1: A new biomarker in pulmonary arterial hypertension." in: Pulmonary circulation, Vol. 3, Issue 1, pp. 74-81, (2013) (PubMed).

Ha, Iqbal, Mita, Ruoff, Gerald, Lepor, Taneja, Lee, Melamed, Garabedian, Logan: "Phosphorylation of the androgen receptor by PIM1 in hormone refractory prostate cancer." in: Oncogene, Vol. 32, Issue 34, pp. 3992-4000, (2013) (PubMed).

Baron, Anastasi, Hyjek, Bies, Reddy, Dong, Joseph, Thirman, Wroblewski, Wolff, Baron: "PIM1 gene cooperates with human BCL6 gene to promote the development of lymphomas." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 15, pp. 5735-9, (2012) (PubMed).

Synonyme und alternative Namen zu PIM1

Pim-1 proto-oncogene, serine/threonine kinase (PIM1), proviral integration site 1 (Pim1), Pim-1 proto-oncogene, serine/threonine kinase (Pim1), Pim-1 proto-oncogene, serine/threonine kinase (pim1), Pim-1 proto-oncogene, serine/threonine kinase L homeolog (pim1.L), PIM, pim, Pim-1, pim-1, PIM1, pim3

Bezeichner auf Proteinebene für PIM1

  • Oncogene PIM1
  • pim-1 kinase 44 kDa isoform
  • pim-1 oncogene (proviral integration site 1)
  • proto-oncogene serine/threonine-protein kinase pim-1
  • serine/threonine-protein kinase pim-1
  • pim-1 oncogene
  • non-specific serine/threonine protein kinase
  • proto-oncogene serine/threonine-protein kinase Pim-1
  • proviral integration site 1
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