LILRB2 Antikörper (C-Term)
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- Target Alle LILRB2 Antikörper anzeigen
- LILRB2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser LILRB2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- MDTRAAASEA PQDVTYAQLH SLTLRRKATE PPPSQEREPP AEPSIYATLA
- Homologie
- Human: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against LILRB2. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product LILRB2 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 598 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- LILRB2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2))
- Andere Bezeichnung
- LILRB2 (LILRB2 Produkte)
- Synonyme
- CD85D antikoerper, ILT-4 antikoerper, ILT4 antikoerper, LIR-2 antikoerper, LIR2 antikoerper, MIR-10 antikoerper, MIR10 antikoerper, leukocyte immunoglobulin-like receptor subfamily A member 3 antikoerper, leukocyte immunoglobulin like receptor B2 antikoerper, LOC100433990 antikoerper, LILRB2 antikoerper
- Hintergrund
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This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CD85D, ILT4, LILRA6, LIR-2, LIR2, MIR-10, MIR10
Protein Interaction Partner: PTPN6, FCGR1A, HLA-F, HLA-G, HLA-C, HLA-B, HLA-A,
Protein Size: 598 - Molekulargewicht
- 65 kDa
- Gen-ID
- 10288
- NCBI Accession
- NM_005874, NP_005865
- UniProt
- Q8N423
- Pathways
- Cellular Response to Molecule of Bacterial Origin
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