LILRB2 Antikörper (AA 51-184)

Produktnummer ABIN5684070

Produktdetails anti-LILRB2 Antikörper

Target: LILRB2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2))

Bindungsspezifität: AA 51-184

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LILRB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human LILRB2 (AA: 51-184) expressed in E. coli.

Klon: 2G7E11

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Details zu LILRB2

Target: LILRB2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2))

Andere Bezeichnung: LILRB2 (LILRB2 Produkte)

Synonyme: CD85D antikoerper, ILT-4 antikoerper, ILT4 antikoerper, LIR-2 antikoerper, LIR2 antikoerper, MIR-10 antikoerper, MIR10 antikoerper, leukocyte immunoglobulin-like receptor subfamily A member 3 antikoerper, leukocyte immunoglobulin like receptor B2 antikoerper, LOC100433990 antikoerper, LILRB2 antikoerper

Hintergrund:

Description: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

Aliases: ILT4, LIR2, CD85D, ILT-4, LIR-2, MIR10, MIR-10

Molekulargewicht: 65 kDa

Gen-ID: 10288

HGNC: 8771

Pathways: Cellular Response to Molecule of Bacterial Origin