LILRB2 Antikörper (AA 1-100)

Produktnummer ABIN1713554

Produktdetails anti-LILRB2 Antikörper

Target: LILRB2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2))

Bindungsspezifität: AA 1-100

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LILRB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LILRB2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu LILRB2

Target: LILRB2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2))

Andere Bezeichnung: LILRB2 (LILRB2 Produkte)

Synonyme: CD85D antikoerper, ILT-4 antikoerper, ILT4 antikoerper, LIR-2 antikoerper, LIR2 antikoerper, MIR-10 antikoerper, MIR10 antikoerper, leukocyte immunoglobulin-like receptor subfamily A member 3 antikoerper, leukocyte immunoglobulin like receptor B2 antikoerper, LOC100433990 antikoerper, LILRB2 antikoerper

Hintergrund:

Synonyms: CD85D, CD85 antigen-like family member D, CD85d, CD85d antigen, ILT 4, ILT-4, ILT4, Immunoglobulin like transcript 4, Immunoglobulin-like transcript 4, Leukocyte immunoglobulin like receptor 2, Leukocyte immunoglobulin like receptor subfamily B member 2, Leukocyte immunoglobulin-like receptor 2, Leukocyte immunoglobulin-like receptor subfamily B member 2, Leukocyte immunoglobulin-like receptor, subfamily B with TM and ITIM domains, member 2, LILRA6, LILRB2, LIR 2, LIR-2, LIR2, LIRb, LIRB2_HUMAN, MIR 10, MIR-10, MIR10, Monocyte/macrophage immunoglobulin like receptor 10, Monocyte/macrophage immunoglobulin-like receptor 10.

Background: Leukocyte immunoglobulin-like receptors (LIRs) are members of the immunoglobulin superfamily of glycoproteins and are predominantly expressed by monocytes, B cells, dendritic cells, natural killer (NK) cells, peripheral blood leukocytes and tissues such as placenta, lung and liver. These receptors all contain a cytoplasmic immunoreceptor tyrosine-based inhibitory motif (ITIM), have an inhibitory function and are type I membrane proteins. When they bind to MHC (or other ligands) and ITIM is tyrosine phosphorylated, protein-tyrosine phosphatases are recruited and an inhibitory signal cascade triggered. ILT-4, also designated LIR-2, MIR-10 or CD85D antigen, competes with CD8A for binding to class I MHC antigens.

Gen-ID: 10288

UniProt: Q8N423

Pathways: Cellular Response to Molecule of Bacterial Origin