LILRB2 Antikörper

Produktnummer ABIN7255946

Produktdetails anti-LILRB2 Antikörper

Target: LILRB2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LILRB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human LILRB2 (NP_005865.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu LILRB2

Target: LILRB2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2))

Andere Bezeichnung: LILRB2 (LILRB2 Produkte)

Synonyme: CD85D antikoerper, ILT-4 antikoerper, ILT4 antikoerper, LIR-2 antikoerper, LIR2 antikoerper, MIR-10 antikoerper, MIR10 antikoerper, leukocyte immunoglobulin-like receptor subfamily A member 3 antikoerper, leukocyte immunoglobulin like receptor B2 antikoerper, LOC100433990 antikoerper, LILRB2 antikoerper

Hintergrund: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht:

Observed_MW: 65 kDa

Calculated_MW: 51 kDa/55 kDa/64 kDa/65 kDa

Gen-ID: 10288

UniProt: Q8N423

Pathways: Cellular Response to Molecule of Bacterial Origin