CIITA Antikörper (C-Term)
-
- Target Alle CIITA Antikörper anzeigen
- CIITA (Class II, Major Histocompatibility Complex, Transactivator (CIITA))
-
Bindungsspezifität
- C-Term
-
Reaktivität
- Human, Maus, Ratte, Hund
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser CIITA Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB)
- Sequenz
- MALWESLQQQ GEAQLLQAAE EKFTIEPFKA KSPKDVEDLD RLVQTQRLRN
- Homologie
- Dog: 100%, Human: 79%, Mouse: 100%, Rat: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against C2TA. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of mouse C2TA
- Top Product
- Discover our top product CIITA Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
-
Antigen size: 1078 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- CIITA (Class II, Major Histocompatibility Complex, Transactivator (CIITA))
- Andere Bezeichnung
- C2TA (CIITA Produkte)
- Synonyme
- CIITA antikoerper, C2ta antikoerper, EG669998 antikoerper, Gm9475 antikoerper, C2TA antikoerper, CIITAIV antikoerper, MHC2TA antikoerper, NLRA antikoerper, Mhc2ta antikoerper, class II, major histocompatibility complex, transactivator antikoerper, class II major histocompatibility complex transactivator antikoerper, MHC class II transactivator antikoerper, class II transactivator antikoerper, CIITA antikoerper, LOC710761 antikoerper, ciita antikoerper, LOC100443575 antikoerper, Ciita antikoerper, LOC100736732 antikoerper
- Hintergrund
-
C2ta is essential for transcriptional activity of the HLA class II promoter, activation is via the proximal promoter. No DNA binding of in vitro translated CIITA was detected. C2ta may act in a coactivator-like fashion through protein-protein interactions by contacting factors binding to the proximal MHC class II promoter, to elements of the transcription machinery, or both. Alternatively it may activate HLA class II transcription by modifying proteins that bind to the MHC class II promoter
Alias Symbols: C2ta, Gm9475, EG669998
Protein Interaction Partner: Rfxank, Ssbp4, Ssbp3, Gmeb1, Cited4, Tcf3, Nfe2, Hoxa2, Ewsr1,
Protein Size: 1078 - Molekulargewicht
- 119 kDa
- Gen-ID
- 12265
- NCBI Accession
- NM_007575, NP_031601
- UniProt
- Q3U2P0
- Pathways
- Cancer Immune Checkpoints
-