Survivin Antikörper (AA 1-142)

Produktnummer ABIN2738580

Produktdetails anti-Survivin Antikörper

Target: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Bindungsspezifität: AA 1-142

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Survivin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: Human BIRC5 / Survivin

Aufreinigung: Immunoaffinity purified

Immunogen: Human recombinant protein (aa M1-D142).

Type of Immunogen: Recombinant protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Approved: ELISA (0.1 - 0.5 μg/mL), IHC, IHC-P (0.5 - 1 μg/mL), WB (0.5 - 1 μg/mL)

Usage: Survivin, also called baculoviral inhibitor of apoptosis repeat-containing 5 or BIRC5, is a protein that, in humans, is encoded by the BIRC5 gene. It is a member of the inhibitor of apoptosis (IAP) family. The gene is mapped to chromosome 17q25 by pulsed field gel electrophoresis and single- and two-color FISH. The Survivin protein functions to inhibit caspase activation, thereby leading to negative regulation of apoptosis or programmed cell death. It is expressed highly in most human tumours and fetal tissue, but is completely absent in terminally differentiated cells.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Sterile distilled water

Konzentration: Lot specific

Buffer: Lyophilized from PBS, 0.025 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze/thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for 1 month or -20°C for longer. Avoid freeze/thaw cycles.

Details zu Survivin

Target: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Andere Bezeichnung: BIRC5 / Survivin (BIRC5 Produkte)

Synonyme: AP14 antikoerper, API4 antikoerper, EPR-1 antikoerper, AAC-11 antikoerper, Api4 antikoerper, TIAP antikoerper, survivin40 antikoerper, bir5a antikoerper, survivin antikoerper, BIR1 antikoerper, Su2 antikoerper, XBIR1 antikoerper, XSurvivin1 antikoerper, Xsvv1 antikoerper, api4 antikoerper, bir1-A antikoerper, epr-1 antikoerper, svv1 antikoerper, xSurvivin antikoerper, xsurv antikoerper, Su1 antikoerper, birc5.2 antikoerper, svv2 antikoerper, xSurvivin2 antikoerper, bir5b antikoerper, SIX antikoerper, birc5.2-a antikoerper, birc5.2-b antikoerper, baculoviral IAP repeat containing 5 antikoerper, baculoviral IAP repeat-containing 5 antikoerper, baculoviral IAP repeat containing 5a antikoerper, baculoviral IAP repeat-containing 5, gene 1 L homeolog antikoerper, baculoviral IAP repeat containing 5 L homeolog antikoerper, baculoviral IAP repeat containing 5b antikoerper, baculoviral IAP repeat containing 5 S homeolog antikoerper, BIRC5 antikoerper, Birc5 antikoerper, birc5a antikoerper, birc5.1.L antikoerper, birc5.2.L antikoerper, birc5b antikoerper, birc5.2.S antikoerper

Hintergrund: Name/Gene ID: BIRC5
Family: Apoptosis

Synonyms: BIRC5, API4, Apoptosis inhibitor survivin, Apoptosis inhibitor 4, Survivin, Survivin variant 3 alpha, EPR-1, IAP4

Gen-ID: 332

Pathways: Apoptose, Zellzyklus, Nuclear Hormone Receptor Binding