PAX5 Antikörper

Produktnummer ABIN271778

Produktdetails anti-PAX5 Antikörper

Target: PAX5 (Paired Box 5 (PAX5))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAX5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody detects endogenous levels of Pax-5 protein. (region surrounding Asp2)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Reinheit: > 95 % pure by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: DO NOT FREEZE!

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu PAX5

Target: PAX5 (Paired Box 5 (PAX5))

Andere Bezeichnung: PAX5 (PAX5 Produkte)

Synonyme: PAX5 antikoerper, BSAP antikoerper, Pax-5 antikoerper, pax5-a antikoerper, RGD1565236 antikoerper, EBB-1 antikoerper, KLP antikoerper, Pax[Zf-b] antikoerper, noi antikoerper, pax2.1 antikoerper, pax2a antikoerper, paxzf-b antikoerper, paired box 5 antikoerper, paired box 5 L homeolog antikoerper, PAX5 antikoerper, pax5.L antikoerper, Pax5 antikoerper, pax5 antikoerper

Hintergrund: The Pax gene family of nuclear transcription factors is comprised of nine family members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. For example, the human Pax-5 gene encodes a B cell lineage specific protein called B cell specific activator protein or BSAP, which is expressed in pro-B, pre-B and mature B lymphocytes but not in plasma cells. BSAP functions to regulate not only B cell development, but also influences the balance between immunoglobulin secretion and B cell proliferation. Overexpression of BSAP has been implicated in cellular transformation, and in the case of small lyphocytic lymphomas with plasmacytoid differentiation, a t(9,14)(p13,q32) translocation resulting in the deregulation of Pax-5 gene expression has been detected. The gene which encodes Pax-5 maps to human chromosome 9p13.Synonyms: B-cell-specific transcription factor, BSAP, Paired box protein Pax-5, Pax-5

Molekulargewicht: approx. 40 kDa

Gen-ID: 5079

NCBI Accession: NP_057953

UniProt: Q02548