PAX5 Antikörper (AA 235-382)

Produktnummer ABIN6940256

Produktdetails anti-PAX5 Antikörper

Target: PAX5 (Paired Box 5 (PAX5))

Bindungsspezifität: AA 235-382

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PAX5 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Staining Methods (StM)

Aufreinigung: Purified by Protein A/G

Immunogen: A recombinant fragment (around aa 235-382) of human PAX5 protein (exact sequence is proprietary)

Klon: PAX5-3735

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: Daudi or Ramos cells. Tonsil, spleen, Lymph Node or Colon Carcinoma.

Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu PAX5

Target: PAX5 (Paired Box 5 (PAX5))

Andere Bezeichnung: PAX5 (PAX5 Produkte)

Synonyme: PAX5 antikoerper, BSAP antikoerper, Pax-5 antikoerper, pax5-a antikoerper, RGD1565236 antikoerper, EBB-1 antikoerper, KLP antikoerper, Pax[Zf-b] antikoerper, noi antikoerper, pax2.1 antikoerper, pax2a antikoerper, paxzf-b antikoerper, paired box 5 antikoerper, paired box 5 L homeolog antikoerper, PAX5 antikoerper, pax5.L antikoerper, Pax5 antikoerper, pax5 antikoerper

Hintergrund: The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 21,000, full-length human proteins. The PAX5 gene is a member of thepaired box (PAX)family of transcription factors. The central feature of this gene family is a novel, highly conservedDNA-binding domain, known as thepaired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute toneoplastic transformation. The PAX5 gene encodes theB-celllineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis, therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development andspermatogenesis.

Molekulargewicht: 42kDa

Gen-ID: 5079

UniProt: Q02548