Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

PAX5 Antikörper (AA 151-306)

PAX5 Reaktivität: Human, Maus WB, IHC, IF, IP Wirt: Maus Monoclonal 24-Pax unconjugated
Produktnummer ABIN968219
  • Target Alle PAX5 Antikörper anzeigen
    PAX5 (Paired Box 5 (PAX5))
    Bindungsspezifität
    • 15
    • 9
    • 8
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 151-306
    Reaktivität
    • 104
    • 53
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 81
    • 16
    • 6
    • 1
    Maus
    Klonalität
    • 70
    • 34
    Monoklonal
    Konjugat
    • 60
    • 8
    • 7
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PAX5 Antikörper ist unkonjugiert
    Applikation
    • 67
    • 47
    • 30
    • 19
    • 16
    • 14
    • 13
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
    Kreuzreaktivität
    Maus
    Produktmerkmale
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    Aufreinigung
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogen
    Human Pax-5 aa. 151-306
    Klon
    24-Pax
    Isotyp
    IgG1
    Top Product
    Discover our top product PAX5 Primärantikörper
  • Kommentare

    Related Products: ABIN968544, ABIN967389

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    250 μg/mL
    Buffer
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store undiluted at -20° C.
  • Klein, Tu, Stolovitzky, Keller, Haddad, Miljkovic, Cattoretti, Califano, Dalla-Favera: "Transcriptional analysis of the B cell germinal center reaction." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 5, pp. 2639-44, (2003) (PubMed).

    Hertel, Zhou, Hamilton-Dutoit, Junker: "Loss of B cell identity correlates with loss of B cell-specific transcription factors in Hodgkin/Reed-Sternberg cells of classical Hodgkin lymphoma." in: Oncogene, Vol. 21, Issue 32, pp. 4908-20, (2002) (PubMed).

    Foss, Reusch, Demel, Lenz, Anagnostopoulos, Hummel, Stein: "Frequent expression of the B-cell-specific activator protein in Reed-Sternberg cells of classical Hodgkin's disease provides further evidence for its B-cell origin." in: Blood, Vol. 94, Issue 9, pp. 3108-13, (1999) (PubMed).

    Zwollo, Arrieta, Ede, Molinder, Desiderio, Pollock: "The Pax-5 gene is alternatively spliced during B-cell development." in: The Journal of biological chemistry, Vol. 272, Issue 15, pp. 10160-8, (1997) (PubMed).

  • Target
    PAX5 (Paired Box 5 (PAX5))
    Andere Bezeichnung
    Pax-5 (PAX5 Produkte)
    Synonyme
    PAX5 antikoerper, BSAP antikoerper, Pax-5 antikoerper, pax5-a antikoerper, RGD1565236 antikoerper, EBB-1 antikoerper, KLP antikoerper, Pax[Zf-b] antikoerper, noi antikoerper, pax2.1 antikoerper, pax2a antikoerper, paxzf-b antikoerper, paired box 5 antikoerper, paired box 5 L homeolog antikoerper, PAX5 antikoerper, pax5.L antikoerper, Pax5 antikoerper, pax5 antikoerper
    Hintergrund
    There are at least nine members of the paired box (Pax) gene family whose protein products are transcription factors involved in development. The conserved paired box DNA-binding domain is found in the N-terminal region of Pax proteins. An octomer and homeodomain sequence are conserved in the center of the proteins. The Ser/Thr/Pro-rich region in the C-terminal portion contains a conserved 100 amino acid transactivating domain. One of the best studied Pax family members, Pax 5, is a B cell specific activator protein (BSAP). In the early stages of B cell development, Pax-5 influences the expression of several B-cell-specific genes, such as CD19 and CD20. Pax-5 is expressed primarily in pro-, pre-, and mature B cells, but not in plasma cells. Interestingly, Pax-5 mRNA is transiently detected in the mesencephalon and spinal cord during embryogenesis. Expression then shifts to the fetal liver and correlates with the onset of B lymphopoiesis. Pax-5 has been found to be important in both B cell and nervous system development. This antibody is routinely tested by western blot analysis.
    Molekulargewicht
    50 kDa
Sie sind hier:
Kundenservice