CD25 Antikörper

Produktnummer ABIN2689120

Produktdetails anti-CD25 Antikörper

Target: CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

Reaktivität: Kaninchen

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD25 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Blocking Reagent (BR)

Marke: BD Pharmingen™

Produktmerkmale: The Kei-α1 antibody reacts with the rabbit homolog of CD25, the interleukin-2 receptor alpha chain (IL-2Rα). mAb Kei-α1 recognizes specifically IL-2Rα and neither the IL-2R ß chain (CD122) nor the 25- kDa protein component of the rabbit high-affinity IL-2R complex. Based on flow cytometric analysis, fewer than 1 % of resting peripheral blood T and B cells have been found to stain with Kei-α1, while a majority of PHA blasts show intense staining with Kei-α1. The HTLV-1-transformed rabbit cell lines, F648b and YR-1 both also show intense staining with Kei-α1. mAb Kei-α1 has been reported to block both high-and low-affinity IL-2 binding and also cell proliferation of rabbit PHA blasts induced by picomolar concentrations of IL-2.

BD Pharmingen™ Purified Mouse Anti-Rabbit CD25 - Purified - Clone Kei-α1 - Isotype Mouse IgG2b, κ - Reactivity Rab - 0.1 mg

Aufreinigung: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogen: Membrane preparation of the HTLV-1-transformed rabbit T-cell line F648b

Klon: Kei

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 4°C.

Referenzen für anti-CD25 Antikörper (ABIN2689120)

Kotani, Yamamura, Tsudo, Tamatani, Kitamura, Miyasaka: "Generation of monoclonal antibodies to the rabbit interleukin-2 receptor alpha chain (CD25) and its distribution in HTLV-1-transformed rabbit T cells." in: Japanese journal of cancer research : Gann, Vol. 84, Issue 7, pp. 770-5, (1993) (PubMed).

Details zu CD25

Target: CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

Andere Bezeichnung: CD25 (IL2RA Produkte)

Synonyme: CD25 antikoerper, IDDM10 antikoerper, IL2R antikoerper, TCGFR antikoerper, IL2RAC antikoerper, IL-2RA antikoerper, Il2r antikoerper, Ly-43 antikoerper, interleukin 2 receptor subunit alpha antikoerper, interleukin-2 receptor subunit alpha-like antikoerper, interleukin 2 receptor, alpha chain antikoerper, IL2RA antikoerper, Il2ra antikoerper, LOC100222957 antikoerper

Hintergrund: Synonyms: IL-2R alpha

Pathways: JAK-STAT Signalweg, Growth Factor Binding, Activated T Cell Proliferation