Retinoblastoma 1 Antikörper (AA 393-572)
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- Target Alle Retinoblastoma 1 (RB1) Antikörper anzeigen
- Retinoblastoma 1 (RB1)
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Bindungsspezifität
- AA 393-572
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Retinoblastoma 1 Antikörper ist unkonjugiert
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Applikation
- Immunoprecipitation (IP)
- Spezifität
- ,Species:Human, Chicken and Mouse.
- Produktmerkmale
- Synonyms: Retinoblastoma 1, Rb, p105-Rb, pRb, pp110, OSRC
- Aufreinigung
- From ascites.
- Immunogen
- Recombinant protein corresponding to amino acids 393 to 572 of the humanretinoblastoma sequence.
- Klon
- XZ104
- Isotyp
- IgG1
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anti-Retinoblastoma 1 (RB1) (C-Term) antibodyRB1 Reaktivität: Human WB, IF, IP, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
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anti-Retinoblastoma 1 (RB1) (pSer780) antibodyRB1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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Immunoprecipitation. This antibody is not recommended for Western blotting or Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS containing 0.08 % Sodium Azide as preservative.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
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Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch. - Haltbarkeit
- 12 months
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- Target
- Retinoblastoma 1 (RB1)
- Andere Bezeichnung
- Retinoblastoma-Associated Protein / RB1 (RB1 Produkte)
- Synonyme
- OSRC antikoerper, RB antikoerper, p105-Rb antikoerper, pRb antikoerper, pp110 antikoerper, Rb antikoerper, Rb-1 antikoerper, P105-RB antikoerper, PP110 antikoerper, RB11 antikoerper, zgc:154147 antikoerper, RB transcriptional corepressor 1 antikoerper, RB transcriptional corepressor like 1 antikoerper, retinoblastoma 1 antikoerper, RB1 antikoerper, RBL1 antikoerper, Rb1 antikoerper, rb1 antikoerper
- Hintergrund
- Retinoblastoma encodes a phosphorylated protein p110 and binds and regulates E2F transcription factors. Rb functions as a major cell cycle regulator by its ability to repress gene transcription by all three RNA polymerases. In its hypophosphorylated form, Rb binds to a subset of E2F containing complexes converting them to repressors preventing expression of E2F target genes. These complexes repress transcription via E2F binding elements in the promotersof cell cycle control genes, such as E2F-1, c-myc, and cdc2 genes.Synonyms: OSRC, Rb, Retinoblastoma 1, p105-Rb, pRb, pp110
- Gen-ID
- 5925
- UniProt
- P06400
- Pathways
- Zellzyklus, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagie
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