TIGIT Antikörper (PE)

Produktnummer ABIN2568497

Produktdetails anti-TIGIT Antikörper (PE)

Target: TIGIT (T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT))

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TIGIT Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Spezifität: The 1G9 monoclonal antibody specifically binds to the mouse TIGIT, expressed on the T helper cells.

Aufreinigung: The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Klon: 1G9

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Lagerung: 4 °C

Informationen zur Lagerung: The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.

Details zu TIGIT

Target: TIGIT (T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT))

Andere Bezeichnung: TIGIT (TIGIT Produkte)

Synonyme: VSIG9 antikoerper, VSTM3 antikoerper, WUCAM antikoerper, ENSMUSG00000071552 antikoerper, Vstm3 antikoerper, RGD1563191 antikoerper, T-cell immunoreceptor with Ig and ITIM domains antikoerper, T cell immunoreceptor with Ig and ITIM domains antikoerper, TIGIT antikoerper, Tigit antikoerper

Hintergrund: The 1G9 monoclonal antibody specifically binds to the mouse TIGIT, expressed on the T helper cells. While in humans it is expressed also on natural killer cells, Treg cells, memory CD4+ and CD8+ T lymphocytes. TIGIT is not expressed on B cells and is upregulated on CD4+ T cells following activation.TIGIT interacts with CD155, and mediates the interaction between natural killer cells or T lymphocytes with APC and fibroblasts and endothelial cells expressing PVR or PVR-like proteins.

Gen-ID: 100043314

UniProt: P86176

Pathways: Cancer Immune Checkpoints