CDK7 Antikörper
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- Target Alle CDK7 Antikörper anzeigen
- CDK7 (Cyclin-Dependent Kinase 7 (CDK7))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CDK7 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Aufreinigung
- Antibody is purified by Protein A/G affinity chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CDK7.
- Top Product
- Discover our top product CDK7 Primärantikörper
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- Applikationshinweise
- CDK7 antibody can be used for detection of CDK7 by ELISA at 1:75000. CDK7 antibody can be used for detection of CDK7 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Konzentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handhabung
- As with any antibody avoid repeat freeze-thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store CDK7 antibody at -20 °C.
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- Target
- CDK7 (Cyclin-Dependent Kinase 7 (CDK7))
- Andere Bezeichnung
- CDK7 (CDK7 Produkte)
- Synonyme
- CAK1 antikoerper, CDKN7 antikoerper, HCAK antikoerper, MO15 antikoerper, STK1 antikoerper, p39MO15 antikoerper, AI323415 antikoerper, AI528512 antikoerper, C230069N13 antikoerper, Cdkn7 antikoerper, Crk4 antikoerper, CD 7 antikoerper, CDK7 antikoerper, CG3319 antikoerper, DmCDK7 antikoerper, DmCdk7 antikoerper, DmMO15 antikoerper, DmMo15 antikoerper, Dmcdk7 antikoerper, Dmel\\CG3319 antikoerper, Mo15 antikoerper, cdk-7 antikoerper, cdk7 antikoerper, dCdk7 antikoerper, p40[MO15] antikoerper, p40MO15 antikoerper, stk1 antikoerper, zgc:85821 antikoerper, cak1 antikoerper, cdkn7 antikoerper, p39mo15 antikoerper, cyclin dependent kinase 7 antikoerper, cyclin-dependent kinase 7 antikoerper, Cyclin-dependent kinase 7 antikoerper, cyclin-dependent kinase 7 L homeolog antikoerper, CDK7 antikoerper, Cdk7 antikoerper, cdk7.L antikoerper, cdk7 antikoerper
- Hintergrund
- Cdk7 is the catalytic subunit of the CDK-activating kinase (CAK) complex, a serine-threonine kinase. CAK activates the cyclin-associated kinases CDC2/CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive carboxyl-terminus domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Cdk7 is involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.
- Molekulargewicht
- 39 kDa
- Gen-ID
- 1022
- NCBI Accession
- NP_001790
- UniProt
- P50613
- Pathways
- Zellzyklus, DNA Reparatur, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, M Phase
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