HSD11B2 Antikörper

Produktnummer ABIN2458581

Produktdetails anti-HSD11B2 Antikörper

Target: HSD11B2 (Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSD11B2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HSD11B2.

Anwendungsinformationen

Applikationshinweise: HSD11B2 antibody can be used for detection of HSD11B2 by ELISA at 1:62500. HSD11B2 antibody can be used for detection of HSD11B2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store HSD11B2 antibody at -20 °C.

Details zu HSD11B2

Target: HSD11B2 (Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2))

Andere Bezeichnung: HSD11B2 (HSD11B2 Produkte)

Synonyme: MGC81883 antikoerper, 11-HSD2 antikoerper, AME antikoerper, AME1 antikoerper, HSD11K antikoerper, HSD2 antikoerper, SDR9C3 antikoerper, 11HSD2 antikoerper, HSD11B2 antikoerper, hydroxysteroid (11-beta) dehydrogenase 2 L homeolog antikoerper, hydroxysteroid 11-beta dehydrogenase 2 antikoerper, hsd11b2.L antikoerper, HSD11B2 antikoerper, Hsd11b2 antikoerper

Hintergrund: HSD11B2 catalyzes the conversion of cortisol to the inactive metabolite cortisone. It modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.

Molekulargewicht: 45 kDa

Gen-ID: 3291

NCBI Accession: NP_000187

UniProt: P80365

Pathways: Steroid Hormone Biosynthesis, Regulation of Systemic Arterial Blood Pressure by Hormones