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HSD11B2 Antikörper

HSD11B2 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7239047
  • Target Alle HSD11B2 Antikörper anzeigen
    HSD11B2 (Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2))
    Reaktivität
    • 44
    • 24
    • 24
    • 16
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 62
    • 4
    • 1
    Kaninchen
    Klonalität
    • 65
    • 2
    Polyklonal
    Konjugat
    • 28
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HSD11B2 Antikörper ist unkonjugiert
    Applikation
    • 54
    • 25
    • 18
    • 17
    • 17
    • 12
    • 7
    • 5
    • 4
    • 3
    • 3
    ELISA, Immunohistochemistry (IHC)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Synthetic peptide of human HSD11B2
    Isotyp
    IgG
    Top Product
    Discover our top product HSD11B2 Primärantikörper
  • Applikationshinweise
    IHC 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.6 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    HSD11B2 (Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2))
    Andere Bezeichnung
    HSD11B2 (HSD11B2 Produkte)
    Synonyme
    MGC81883 antikoerper, 11-HSD2 antikoerper, AME antikoerper, AME1 antikoerper, HSD11K antikoerper, HSD2 antikoerper, SDR9C3 antikoerper, 11HSD2 antikoerper, HSD11B2 antikoerper, hydroxysteroid (11-beta) dehydrogenase 2 L homeolog antikoerper, hydroxysteroid 11-beta dehydrogenase 2 antikoerper, hsd11b2.L antikoerper, HSD11B2 antikoerper, Hsd11b2 antikoerper
    Hintergrund
    There are at least two isozymes of the corticosteroid 11-beta-dehydrogenase, a microsomal enzyme complex responsible for the interconversion of cortisol and cortisone. The type I isozyme has both 11-beta-dehydrogenase (cortisol to cortisone) and 11-oxoreductase (cortisone to cortisol) activities. The type II isozyme, encoded by this gene, has only 11-beta-dehydrogenase activity. In aldosterone-selective epithelial tissues such as the kidney, the type II isozyme catalyzes the glucocorticoid cortisol to the inactive metabolite cortisone, thus preventing illicit activation of the mineralocorticoid receptor.
    NCBI Accession
    NP_000187
    UniProt
    P80365
    Pathways
    Steroid Hormone Biosynthesis, Regulation of Systemic Arterial Blood Pressure by Hormones
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