HSD11B2 Antikörper (N-Term)

Produktnummer ABIN2776772

Der Kaninchen Polyklonal anti-HSD11B2 Antikörper wird verwendet zum Nachweis von HSD11B2 in Proben von Human, Ratte, Maus, Rind (Kuh), Meerschweinchen, Kaninchen, Schaf und Pferd. Er wurde validiert für WB.

Kurzübersicht für HSD11B2 Antikörper (N-Term) (ABIN2776772)

Target: HSD11B2 (Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Meerschweinchen, Kaninchen, Schaf, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSD11B2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HSD11B2 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: HSD11B2 Antibody - N-terminal region

Sequenz: ERWPWPSGGA WLLVAARALL QLLRSDLRLG RPLLAALALL AALDWLCQRL

Homologie: Cow: 100%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against HSD11B2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HSD11B2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41372-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu HSD11B2

Target: HSD11B2 (Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2))

Andere Bezeichnung: HSD11B2

Hintergrund:

Background Information: HSD11B2 catalyzes the conversion of cortisol to the inactive metabolite cortisone. It modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.

Gene Name: Hydroxysteroid (11-beta) dehydrogenase 2

Alternative Symbols: AME, AME1, HSD2, HSD11K, SDR9C3

Protein Name: Corticosteroid 11-beta-dehydrogenase isozyme 2

Molekulargewicht: 45kDa

Gen-ID: 3291

NCBI Accession: NP_000187

UniProt: P80365

Pathways: Steroid Hormone Biosynthesis, Regulation of Systemic Arterial Blood Pressure by Hormones