Retinoblastoma Binding Protein 8 Antikörper (Center)

Produktnummer ABIN1887524

Produktdetails anti-Retinoblastoma Binding Protein 8 Antikörper

Target: Retinoblastoma Binding Protein 8 (RBBP8)

Bindungsspezifität: Center

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Retinoblastoma Binding Protein 8 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 14 amino acid peptide near the center of human RBBP8.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu Retinoblastoma Binding Protein 8

Target: Retinoblastoma Binding Protein 8 (RBBP8)

Andere Bezeichnung: RBBP8 (RBBP8 Produkte)

Synonyme: COM1 antikoerper, CTIP antikoerper, JWDS antikoerper, RIM antikoerper, SAE2 antikoerper, SCKL2 antikoerper, 9930104E21Rik antikoerper, CtIP antikoerper, RBBP-8 antikoerper, RGD1308872 antikoerper, RBBP8 antikoerper, DKFZp469K0714 antikoerper, RB binding protein 8, endonuclease antikoerper, retinoblastoma binding protein 8, endonuclease antikoerper, retinoblastoma binding protein 8 L homeolog antikoerper, retinoblastoma binding protein 8 antikoerper, RBBP8 antikoerper, Rbbp8 antikoerper, rbbp8.L antikoerper, rbbp8 antikoerper

Hintergrund: RBBP8, also known as CtBP (carboxy-terminal binding protein) interacting protein (CTIP), was characterized for its role in transcription as a cofactor for the transcriptional repressor CtBP, and also as a binding partner for other proteins including the cell cycle regulators retinoblastoma protein (Rb) and breast cancer 1 (BRCA1).It is ubiquitously expressed and localizes to the nucleus.RBBP8 is thought to modulate the functions in cell proliferation, transcriptional regulation and DNA repair.RBBP8 also plays a central role in the cell cycle checkpoint response to DNA double-stranded breaks (DSBs), with new evidence demonstrating that it controls the choice of DSB repair pathway.
Synonyms: Retinoblastoma-binding protein 8, CTIP, CtBP-interacting protein, RIM

NCBI Accession: NP_976037

Pathways: Zellzyklus, DNA Reparatur