Retinoblastoma Binding Protein 8 Antikörper (AA 1-300)

Produktnummer ABIN6146750

Produktdetails anti-Retinoblastoma Binding Protein 8 Antikörper

Target: Retinoblastoma Binding Protein 8 (RBBP8)

Bindungsspezifität: AA 1-300

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Retinoblastoma Binding Protein 8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MNISGSSCGS PNSADTSSDF KDLWTKLKEC HDREVQGLQV KVTKLKQERI LDAQRLEEFF TKNQQLREQQ KVLHETIKVL EDRLRAGLCD RCAVTEEHMR KKQQEFENIR QQNLKLITEL MNERNTLQEE NKKLSEQLQQ KIENDQQHQA AELECEEDVI PDSPITAFSF SGVNRLRRKE NPHVRYIEQT HTKLEHSVCA NEMRKVSKSS THPQHNPNEN EILVADTYDQ SQSPMAKAHG TSSYTPDKSS FNLATVVAET LGLGVQEESE TQGPMSPLGD ELYHCLEGNH KKQPFEESTR

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human RBBP8 (NP_976036.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Retinoblastoma Binding Protein 8

Target: Retinoblastoma Binding Protein 8 (RBBP8)

Andere Bezeichnung: RBBP8 (RBBP8 Produkte)

Synonyme: COM1 antikoerper, CTIP antikoerper, JWDS antikoerper, RIM antikoerper, SAE2 antikoerper, SCKL2 antikoerper, 9930104E21Rik antikoerper, CtIP antikoerper, RBBP-8 antikoerper, RGD1308872 antikoerper, RBBP8 antikoerper, DKFZp469K0714 antikoerper, RB binding protein 8, endonuclease antikoerper, retinoblastoma binding protein 8, endonuclease antikoerper, retinoblastoma binding protein 8 L homeolog antikoerper, retinoblastoma binding protein 8 antikoerper, RBBP8 antikoerper, Rbbp8 antikoerper, rbbp8.L antikoerper, rbbp8 antikoerper

Hintergrund: The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.,RBBP8,COM1,CTIP,JWDS,RIM,SAE2,SCKL2,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cancer,Tumor suppressors,RBBP8

Molekulargewicht: 98 kDa/101 kDa/102 kDa

Gen-ID: 5932

UniProt: Q99708

Pathways: Zellzyklus, DNA Reparatur