SARM1 Antikörper (C-Term)

Produktnummer ABIN1887395

Produktdetails anti-SARM1 Antikörper

Target: SARM1 (Sterile alpha and TIR Motif Containing 1 (SARM1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SARM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Aufreinigung: Ion exchange chromatography purified

Immunogen: Peptide corresponding to amino acids near the C-terminus of human SARM.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu SARM1

Target: SARM1 (Sterile alpha and TIR Motif Containing 1 (SARM1))

Andere Bezeichnung: SARM (SARM1 Produkte)

Synonyme: A830091I15Rik antikoerper, C78606 antikoerper, MyD885 antikoerper, Sarm antikoerper, MyD88-5 antikoerper, SAMD2 antikoerper, SARM antikoerper, sterile alpha and TIR motif containing 1 antikoerper, sterile alpha and HEAT/Armadillo motif containing 1 antikoerper, SARM1 antikoerper, Sarm1 antikoerper, sarm1 antikoerper

Hintergrund: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses.SARM (SAM and ARM-containing protein), along with other molecules such as TIRP, TRIF, TIRAP, and MyD88, is thought to serve as an adaptor protein for the TLRs that allows for the activation of downstream kinases and NF-kappaB, and ultimately the expression of proteins involved in host defense.While SARM has not been conclusively shown to associate directly with TLRs, the presence of a Toll-interluekin-1 (TIR) domain in SARM is consistent with a role as a signaling molecule.

NCBI Accession: NP_055892

Pathways: TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades