TLR5 Antikörper (C-Term)

Produktnummer ABIN1887381

Produktdetails anti-TLR5 Antikörper

Target: TLR5 (Toll-Like Receptor 5 (TLR5))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLR5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Peptide corresponding to 15 amino acids near the carboxy terminus of human TLR5.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu TLR5

Target: TLR5 (Toll-Like Receptor 5 (TLR5))

Andere Bezeichnung: TLR5 (TLR5 Produkte)

Synonyme: SLEB1 antikoerper, TIL3 antikoerper, TLR-5 antikoerper, sleb1 antikoerper, til3 antikoerper, tlr-5 antikoerper, tlr5 antikoerper, toll like receptor 5 antikoerper, toll-like receptor 5 antikoerper, toll like receptor 5 L homeolog antikoerper, toll-like receptor 5b antikoerper, TLR5 antikoerper, Tlr5 antikoerper, tlr5.L antikoerper, tlr-5 antikoerper, tlr5b antikoerper

Hintergrund: Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila.These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses.The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors so the organism can respond to potential infection.TLR5 recognizes flagellin from both Gram-positive and Gram-negative bacteria and will cause the activation of NF-kappaB, leading to the activation of TNF-alpha and other cytokines.A common TLR5 stop codon polymorphism that disrupts TLR5 signaling is associated with susceptibility to Legionnaires' disease and demonstrates the importance of TLR5 in the innate immune response.
Synonyms: Toll-like receptor 5

NCBI Accession: NP_003259

Pathways: TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades