FGF4 Antikörper (C-Term)

Produktnummer ABIN1887254

Produktdetails anti-FGF4 Antikörper

Target: FGF4 (Fibroblast Growth Factor 4 (FGF4))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FGF4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 18 amino acid peptide near the carboxy terminus of the human FGF4.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu FGF4

Target: FGF4 (Fibroblast Growth Factor 4 (FGF4))

Andere Bezeichnung: FGF4 (FGF4 Produkte)

Synonyme: HBGF-4 antikoerper, HST antikoerper, HST-1 antikoerper, HSTF1 antikoerper, K-FGF antikoerper, KFGF antikoerper, Fgf-4 antikoerper, Fgfk antikoerper, Hst1 antikoerper, Hstf-1 antikoerper, KS3 antikoerper, hst antikoerper, hst-1 antikoerper, kFGF antikoerper, Hst antikoerper, fibroblast growth factor 4 antikoerper, FGF4 antikoerper, Fgf4 antikoerper

Hintergrund: Fibroblast growth factor 4 (FGF4) is a member of the fibroblast growth factor (FGF) family that possess broad mitogenic and cell survival activities and play key roles in growth and survival of stem cells during embryogenesis, tissue regeneration, and carcinogenesis.FGF4 was identified by its strong oncogenic transforming activity and is a potent angiogenic factor, expressed in several highly vascularized tumors and also in adult mouse testis, intestine, and brain.Studies on the mouse homolog suggests a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway.Furthermore, FGF4 regulates neural progenitor cell proliferation and neuronal differentiation.Recent studies show a growth-promoting role for FGF4 in human embryonic stem cells and a putative feedback inhibition mechanism by a novel FGF4 splice isoform that may serve to promote differentiation at a later stages of development.
Synonyms: Fibroblast growth factor 4, Heparin secretory-transforming protein, HST-1, HST, Transforming protein KS3, HBGF-4, Kaposi sarcoma oncogene

UniProt: P08620

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance